The current eco-social crisis includes global challenges such as climate change, environmental degradation and demographic shifts that call for a global response. The European Environment Agency claims that over the next decade, very different answers will be needed to the world’s challenges than the ones provided over the past 40 years to confront the foreseeable global changes. Higher Education Institutions have their own responsibility in training future professionals in cross-cutting key competences for sustainability, which are defined through different frameworks. Considering that current students will need to overcome global challenges, this research aims to identify the ways in which Higher Education Institutions are anticipating the introduction of key competences for sustainability into the curricula of their programs. Specifically, it aims to detect the perception of the heads of three departments and three faculties of two universities in Spain and Portugal about the presence of key competences for sustainability in the selected degrees. For this study, a qualitative research approach was employed. The methodology used involved the application of interviews to departments and faculties heads. The results showed there is a growing interest in sustainability at Higher Education Institutions, but key competences for sustainability were not yet sufficiently valued as competences needed for the students in the future, in particular those linked with the professional world. Further similar research could be conducted at other levels (master’s degree, doctorate).