Cu analyses by square‐wave voltammetry (SWV) and potentiometric stripping analysis (PSA) using Hg electrodes have been carried out in samples of animal (dog, pig) cerebrospinal fluid (CSF) using media modified with EN (ethylenediamine), N‐MET‐EN (n‐methyl‐ethylenediamine) and DENTRI (diethylenetriamine), taking advantage of the complexing capacity of these reagents towards Cu. Except for the addition just mentioned samples were analyzed with no previous treatment. To confirm the results obtained, a study of these samples through atomic absorption spectrometry (AAS) and the aforementioned techniques (SWV, PSA) were carried out, now with a previous treatment in high pressure acid (HPA). The recommended analytical procedures require times less than 15 minutes and sample volumes less than 50 μL. Besides this, the reliability of the results makes these procedures quite appropriate for medical purposes.

No abstract