To respond to rapidly growing demands for clinical research at the local level, it is important to build robust research infrastructure in low-and middle-income countries. The 2014-2015 Ebola outbreak in West Africa revealed the lack of infrastructure, expertise, and regulations in the face of an urgent need for clinical trials at the local level during public health crises (1). The number and complexity of clinical trials have increased significantly in recent years. According to ClinicalTrials. gov, a registry of clinical studies conducted worldwide in 220 countries, the number of registered clinical studies is rising from 325,773 in 2019-2020 to 362,505 in 2020-2021 (2). The complexity of clinical trials has also increased, particularly since the novel coronavirus infection (COVID-19) pandemic. Consequently, the demand for clinical research professionals exceeds availability, and global efforts to increase the clinical research workforce are underway (3).International cooperation in clinical research is essential for addressing common global health issues and enabling the provision of evidence-based solutions to patients and health professionals in a timely manner. In the face of the COVID-19 pandemic, the need for global cooperation in clinical research to overcome unprecedented health challenges has been reaffirmed. However, multinational research is complex due to differences in regulatory and ethical requirements, medical systems, health priorities, and cultures between countries. These barriers affect the scope of research (247)
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