Introduction: Subclavian artery injury secondary to blunt trauma is rare. Most patients with blunt trauma that affects the major vessels die before reaching the hospital due to trauma kinematics. Appropriate intervention requires immediate identification and proper surgical approach. The intraoperative diagnosis is more common due to the hemodynamic instability of most patients; however, conventional angiography and computed tomography (CT) angiography are also useful diagnostic modalities in stable patients to determine the location of the injury prior to surgery. We present a case of blunt trauma associated with situs inversus totalis which is a rare congenital condition characterized by complete transposition of the thoracic and abdominal viscera.