It has been 10 years since the start of the Syrian uprisings. While relative stability is improving overall, a new disaster, wildfires, impacted an already food-insecure population by burning through key production areas, damaging crops, soil, and livestock and causing air quality to deteriorate. As observed with remotely sensed data, fire affected 4.8% of Syria in 2019, as compared with the average 0.2%, and most fires were observed within agricultural land in the northeast. Abnormal amounts of rainfall during the 2019 growing season and, consequently, high soil moisture explained about 62% of the drastic increase in the burned area extent. In contrast, in 2020, fires continued despite the average amount of rainfall. Extremely high temperature could partially explain a 10-fold increase in the extent of burned area in 2020 but only within forested regions in the northwest. We argue that the abrupt changes in Syria’s fire activity were driven by the complex interactions among conflict, migration, land use, and climate. On one side, the ongoing conflict leads to a drastic increase in the number of accidental and deliberate fires and reduced capacity for fire response. On the other side, years of insecurity, widespread displacement, and economic instability left no choice for locals other than exploiting fires to remove natural vegetation for expanding farming, logging, and charcoal trading. The loss of agricultural production and natural vegetation to fire can have serious implications for food security, soil property, biodiversity, and ecosystem services, which can further exacerbate the already unstable economy and make ongoing violence even more intense.