The case of a 43-y-old healthy woman presenting with spontaneous splenic rupture is reported. The outcome was favourable after splenectomy. Although the diagnosis of CMV infection was established by serology, PCR and immunostaining, no viral inclusions were observed on spleen sections. The pathophysiology of the lesions was unclear given the multiple interactions of the virus with various cell populations, and particularly with the immune system.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.