Accidental envenomation caused by Tityus serrulatus scorpions is very common in Brazil and may result in serious cardiorespiratory alterations that are frequently fatal to children. In the present study, the effects of T. serrulatus venom on the cardiorespiratory system of recently weaned male Wistar rats were evaluated. Fifteen animals were distributed into three groups (n = 5). The control group A received 400 μL ultrapure water by subcutaneous injection, while the experimental groups B and C were injected with scorpion venom (100 and 450 μg, respectively, in 400 μL water). Electrocardiogram (ECG) traces were obtained prior to the experiment, at five-minute intervals up to 30 minutes after treatment. At 40 minutes after envenomation, the animals had severe acute symptoms and were subsequently anesthetized for blood collection by means of intracardiac puncture. Biochemical profiles for the cardiac muscle were established by colorimetric analysis of creatine kinase (CK) and CK-MB isoenzyme. Semiquantitative analysis of troponin was performed using the immunochromatographic assay. Following euthanasia, the lungs and hearts were removed and subjected to histopathological examination. All experimental animals had ECG alterations compatible with electrolytic imbalance, myocarditis and alterations of the cardiac conduction system. Envenomed animals had accentuated bradycardia at 25 and 30 minutes after venom inoculation. All experimental animals had myocardial lesions, which were confirmed by increased serum levels of CK and CK-MB, although there were no alterations in the serum concentration of troponin. Pulmonary hemorrhage was detected in whole lungs and microscopically confirmed by the presence of congested capillaries and erythrocytes in the alveolar parenchyma. In conclusion, T. serrulatus venom caused great cardiorespiratory damage to weaned rats.

Doutor em Ciências Sociais e Humanas pela Universidad Nacional de QuilmesProfessor da Universidade Estadual do Sudoeste da Bahia (UESB/Brasil) __________________________________________________________________________________ A B S T R A C TOur direct experience in a teacher training course has led us to investigate the practice of the in-training teachers and what they take into consideration (who they interact with) while conducting their classes. The analysis of relations that run through the in-training teacher practice was based on the "pedagogic device" proposed by Basil Bernstein. The in-training teachers' actions in the conduction of their classes on Chemical Bonds were the main focus of this study. The classes were planned based on contemporary teaching trends and some specific instructions which were emphasized during planning. We observed that despite the joint planning of classes, the classes were conducted in different ways by the participants. Half of the participants followed the class plan with minor changes and the other half chose to adopt a class model according to what they had learned in the teacher training course or based on their own experience as students. The investigated students validated some practices that require teacher trainers to perceive and think over. INTRODUÇÃOA Ciência Química se dedica ao estudo do mundo material, principalmente no que tange às suas propriedades, constituição e transformações. Nesse sentido, faz uso de entidades abstratas (átomos, íons, moléculas e outros) e de inúmeros conceitos científicos que contribuem para criar um imaginário de Ciência complexa e de difícil entendimento. Ao ensinar essa Ciência na escola, torna-se importante significar alguns conceitos básicos para que o estudante possa avançar no aprendizado.