Introduction: The climacteric is the stage of life in which the transition from the productive or fertile period to the non-reproductive period occurs. Climacteric and menopause are intrinsically linked and may bring about various psychological and physiological changes. The use of medicinal plants (Herbal Medicine) is an important tool in an attempt to relieve symptoms. Objective: It was to develop a systematic review to present the main considerations and scientific evidence of the use of herbal medicines in climacteric and menopause to the reduction of symptoms and improvement of quality of life. Methods: The systematic review rules (PRISMA) were followed. The research was carried out from September to October 2022 in the Scopus, PubMed, Science Direct, Scielo, and Google Scholar databases, covering scientific articles from various eras to the present day. The quality of the studies was based on the GRADE instrument and the risk of bias was analyzed according to the Cochrane instrument. Results and Conclusion: A total of 121 articles were found. A total of 32 articles were fully evaluated and 23 were included in this systematic review. Most studies showed homogeneity in their results, with I2 =96.7% >50%. Considering the Cochrane tool for risk of bias, the overall assessment resulted in 30 studies with a high risk of bias and 37 studies that did not meet GRADE. An asymmetrical funnel plot does not suggest a risk of bias among small sample-size studies. In search of symptom relief and based on knowledge of the side effects of hormone replacement therapy, many women resort to alternative therapy with herbal medicines. The main results support that supplementation with soy isoflavones as a natural source of phytohormones is associated with a reduction in the frequency and intensity of hot flashes, a recurrent symptom in the climacteric. The formulated blend of four herbal extracts (Glycine max, Cimicifuga racemosa, Vitex agnus-castus, and Oenothera biennis) supports skin health and antioxidant status in women of menopausal age. Furthermore, purified pollen cytoplasm can be considered an effective non-hormonal treatment alternative for the treatment of vasomotor symptoms, as well as mood and sleep disturbances in peri and post-menopause. Three clinical trials using the Danggui Buxue Tang herbal formula have been shown to alleviate menopausal syndrome, providing solid scientific evidence of its effectiveness.

Introduction: Metabolic syndrome is the association of chronic diseases related to diet and physical activity. Also recognized as a complex entity that associates well-established cardiovascular risk factors, such as hypertension, hypercholesterolemia, and diabetes, among others, with central fat deposition and insulin resistance. Currently, Metabolic Syndrome has gained disturbing dimensions within clinical practice, becoming one of the greatest challenges at the beginning of this century. In contrast, the Mediterranean diet recognized by the combination of a tasty palate and nutritional benefits, in addition to the culture of its link between health and longevity is a strategy in the treatment of metabolic syndrome. Although there is no consensus on the most adequate nutritional strategy to treat Metabolic Syndrome (MS) in a way that reduces cardiovascular risk, recent studies show the efficacy of adopting healthy lifestyles capable of reversing this trend. Objective: To address the role of diet in MS therapy, with a primary focus on the interaction of the benefits of different nutritional interventions in the remission of MS, contributing to the integration of the current evidence in the preexisting context. Methods: The model followed for the systematic review was PRISMA. The search strategy was carried out in the databases PubMed, Embase, Ovid and Cochrane Library, Web Of Science, Science Direct Journals (Elsevier), Scopus (Elsevier), and OneFile (Gale), from September to November 2022, with articles in the last years. Results and Conclusion: In light of the studies carried out in the research it was found that the Mediterranean diet has shown benefits in the secondary prevention of this syndrome, although the underlying mechanisms are not completely clear. It is important to revitalize and apply this diet in the future in terms of preventive and therapeutic guidelines.