Comparison of point of care capillary international normalized ratio (INR) with INR measured in venous samples Background: INR is used to monitor the treatment with vitamin K antagonists. A strategy to reduce waiting times for sampling is to measure INR in a capillary sample using a portable point of care (POC) type coagulometer. Aim: To evaluate the correlation of CoaguChek Pro II TM , Xprecia TM and microINR TM with venous INR measured at the clinical laboratory and their ease of use. Materials and Methods: Patients provided capillary and venous blood samples for parallel tests comparing Xprecia TM Stride with CoaguChek Pro II TM and with venous INR, mi-croINR TM with CoaguChek Pro IITM and with venous INR. The devices' ease of use was assessed surveying the sampling staff. Results: The three tested devices had good correlation coefficients with venous INR: Coa-guChek Pro IITM 0.953 and 0.962; Xprecia TM of 0.912 and microINR TM of 0.932. The correlation coefficient of Xprecia TM with CoaguChek Pro IITM was 0.937 and microINR TM with CoaguChek Pro IITM was 0.976. Conclusions: CoaguChek Pro IITM, Xprecia TM and microINR TM results had a good correlation coefficient with INR measured at the laboratory. Our results indicate that, in the hands of trained users, POC-type coagulometers are reliable and acceptable for routine use in anticoagulant treatment control.
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