Alerts: Sign up at www.eneuro.org/alerts to receive customized email alerts when the fully formatted version of this article is published.
Manuscript Title (50 word maximum)Development of eight wireless automated cages system with two lick-o-meters each for rodents
Abbreviated Title (50 character maximum)Development of wireless lick-o-meter device for rodents 3. List all Author Names and Affiliations in order as they would appear in the
Flavonoids are potential group of phytochemicals found in normal diets capable of mediating improvements in cognition and may reverse age-related declines in memory. Aging is associated with alteration of hippocampal synaptic plasticity and contribute to decline in cognitive functions. The current studies are directed at a greater understanding of how and why the brain modifies synaptic strength with dietary-derived phytochemicals (flavonoids) and age-related declines in cognitive functions (such as learning and memory). Flavonoids modulate neuronal function and thereby influence cognition. In addition, it has been suggested that flavonoids may delay the development of Alzheimer's diseaselike pathology, anxiety, and depression disorders, suggesting a novel therapeutic strategy. Emerging evidence suggest that flavonoids are modulators of signaling pathways critical for controlling synaptic plasticity in the brain. For example, phosphatidylinositol-3 kinase (PI3K)/Akt, mitogen-activated protein kinase, protein kinase C, pathways could be involved Ca 2+ signaling. Significants questions such as: (i) How does flavonoids affect plasticity? (ii) What receptors are modulating by flavonoids and how are they regulated? (iii) Do flavonoids have a neuroprotective effect in aging? are asked.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.