In the mobile pre-hospital environment such as the SAMU, the nurse has several functions in the areas of care, administration, operation and supervision, and must participate in the review of protocols and provide training for the other professionals in the team. Despite this, changes have been taking place over the years in relation to the performance of nursing, improving legal aspects and increasing the autonomy of nurses. The general objective of the research is to analyze the role of nurses in urgent and emergency mobile pre-hospital care, and as specific objectives to describe the nurse's attributions as a member of the urgent and emergency mobile PHC service team, to point out the difficulties and challenges exist in the nurse's work and discuss the importance of the nurse in the mobile emergency APH. Thus, the present work is an integrative literature review, using the following descriptors: “emergency assistance”, “pre-hospital care” and “emergency nursing”. The work was prepared between February and May 2022, using studies published between 2012 and 2022. Such works were found in the SCIELO, LILACS and MEDLINE databases. As a result, the nurse must act as an advisor by participating in the review of protocols, in the elaboration and organization of educational content and as a professional of the multidisciplinary team of accidents and disasters. However, the nurse in the PHC has been exposed to unfavorable ergonomics, low salaries, exhausting workload, influencing their physical and mental health. Thus, the role of nurses in the PHC is still fragmented, developing little autonomy, despite being extremely important in the composition of the team, as it promotes assistance, management, education, leadership and humanization. Still, the need for continuing education with realistic theoretical-practical training for SAMU nurses was proved, with an emphasis on mental health for patients in psychiatric crisis.