In acute quadriplegia we have noted that about one in five patients develops unexplained production of markedly excessive and tenacious bronchial mucus. Spontaneous recovery from mucus hypersecretion usually occurs within weeks to months. Mucus samples collected from 12 patients have been found to be abnormal. Macromolecular contents of single aspirates yielded as much as 500 mg. Analytical ultracentrifuge analysis showed the mucus to contain considerable epithelial glycoprotein (GP) of typical buoyant density; its amino acid and carbohydrate compositions were characteristic of the GP from hypersecretory bronchial mucus such as in chronic bronchitis and cystic fibrosis. In five patients studied after recovery from hypersecretion, there tended to be relatively less GP. The mucus samples contained a high density glycoconjugate (GC): this had sugars of GP but also reacted positively with a monoclonal antibody to keratan sulfate. Its amino acid composition was different from that of GP: threonine was lower and glycine was higher than in GP. In mucus from one patient who died, chondroitin sulfate ABC and hyaluronic acid were identified as well. This suggests proteoglycans are involved in the pathophysiology of mucus hypersecretion. The sudden onset and spontaneous recovery of hypersecretion suggests that it is not due to gland hypertrophy. We speculate that in acute quadriplegia it is due to disturbed neuronal control of bronchial mucus gland secretion, perhaps related to initial disappearance and later reappearance of peripheral sympathetic nervous system tone.

Many Americans believe free trade destroyed the U.S. industrial base, and blame foreign workers for taking their jobs. During World War II, Keynes had similar misgivings about the effect of postwar free trade on Britain’s economy. Yet for Keynes, economic forces are never inevitable, and capital rather than labor was the cause of trouble. His 1941 proposal for an International Clearing Union suggested capital controls, forced creditor adjustment, and an international fiat reserve as remedies for deindustrialization. This framework channeled financing toward production rather than speculation, leading to a rising standard of living for workers. A counterfactual with balance of payments data for the United States and China since 1982 suggests his ICU would have prevented U.S. deindustrialization, while yet permitting export-led growth in China.

For exploitation by capital, Karl Marx 1990 argued, workers must be free in the double sense – free of possessions, but also politically free. Yet, the 19th‐century situation that Marx analyzed included Irish immigrants who formed a subsection of the British working class with fewer political rights. Marx began with a discussion of how economic growth under capitalism creates unemployment, which evolved into a discussion of five components of the working class: army of labor, floating reserve, stagnant pool, latent reserve, and paupers. While Marx never explicitly mentioned the lack of political rights, he did suggest that Irish migrants in the British working class were trapped in precarious stagnant pool jobs. This essay will examine Marx's theory of the multisector reserve army, and draw out the political implications for undocumented immigrants in modern advanced economies.

Conventional wisdom has it that, in the eighteenth century, California’s mission Indians labored without recompense to support the Spanish military and other costs of imperial administration. This article challenges this conventional wisdom, arguing that it was not until the Spanish empire unraveled in the nineteenth century that Indians labored at missions with little compensation. Spain stopped subsidizing California in 1810, at which point the systematic non-payment of Christian Indians for goods supplied to the California military was implemented as an emergency measure. In 1825, independent Mexico finally sent a new governor to California, but military payroll was never reinstated in its entirety. Not surprisingly, most accounts of military confrontation between California Indians and combined mission/military forces date from the 1810 to 1824 period. By investigating an underutilized source—account books of exports and imports for four missions—the article explores two issues: first, the processes of cooptation inside missions up to 1809, and secondly, the way that Spain’s cessation of financing in 1810 affected the relationship with Indians.

No abstract