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During the colU'se of experiments ::m the longevity of female rats that t•iad been :~iven sublethal a11ounts of At 211 , 2 Hamilton et al. (l) foWld a striking incidence ::>f marn.rna.ry tumors. Shellabarger et al. (3) and .Bi:Jlla'll!Tler et al~ (4) subsequentl:r demonstrated increased iucidence of ma~nary tumor in female rats of several straL~s after either sublethal doses of whole.;.bod;~ x-ray_or lethal x-ray doses in animals protected fr::>m acute irradiation death by parabiosis. Croukite et al. (5) have recently sh-:Jw-n that mammary tumor induction is proportional to the x-ra:,-dose, and that immature irradiated rats develop more mam;narr. turnrs than rats irradiated at maturitt• Their data further suggest that ovarian function is an~ther important factor in mammary tumor pro-• duction in irradiated rats. 'fhis re?ort augments previous observations on mammary tumor incidence and, in addition, descril.>es other neoplasms
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