Frontal fibrosing alopecia is a variant of lichen planopilaris with marginal
progressive hair loss on the scalp, eyebrows and axillae. We report a case of
frontal fibrosing alopecia and lichen planus pigmentosus in a postmenopausal
woman, that started with alopecia on the eyebrows and then on the frontoparietal
region, with periocular and cervical hyperpigmentation of difficult management.
The condition was controlled with systemic corticosteroid therapy and
finasteride. Lichen planus pigmentosus is an uncommon variant of lichen planus
frequently associated with frontal fibrosing alopecia in darker phototipes. It
should be considered in patients affected by scarring alopecia with a pattern of
lichen planopilaris and areas of skin hyperpigmentation revealing perifollicular
hyperpigmentation refractory to multiple treatments. This case illustrates
diagnostic and therapeutic challenge in face of scarring alopecia and
perifollicular hyperpigmentation.
BACKGROUNDMelanoma is one of the conditions with greater increase in incidence
worldwide in recent decades. It is a skin cancer with potential high
lethality and predominates in Caucasian adults. Treatment of primary
cutaneous melanoma is essentially surgical and search for sentinel lymph
node can modify the aggressiveness of the treatment.OBJECTIVETo analyze the epidemiological profile of patients diagnosed with primary
cutaneous melanoma, histopathological features and compare with literature
data.METHODSThis is a retrospective, observational, single-center, case series study of
patients with primary cutaneous melanoma, who underwent surgery between
January 2008 and December 2013. The parameters include: Age, sex, clinical
stage, date of surgery, tumor location, histological subtype, condition of
surgical margins, Breslow thickness, mitotic index, presence of ulceration
and metastasis on admission.RESULTSWe included 321 melanoma patients who were treated at Hospital Erasto
Gaertner. The population consisted of 58.9% females and 41.1% males with an
average age of 52.8 ± 16.3 years. As for the clinical stage, 51.1%
were in the initial stage, 24.3% in the clinical stage II (A, B and C),
21.2% in clinical stage III and 3.4% with distant metastases. The most
frequent location of the primary melanoma was the trunk, and the
histological subtype was superficial spreading pattern. Intermediate and
thick melanomas were the most frequent.STUDY LIMITATIONSThis is a retrospective study and some information and data could be
incomplete or absent.CONCLUSIONThe diagnosis and treatment of melanoma in early stages provides less
morbidity and improved survival of patients. Understanding the biological
behavior of tumor and knowing the local epidemiology guide health
strategies.
Carcinoma basocelular na vulva: um relato de caso de neoplasia cutânea em área especial Basal cell carcinoma of the vulva: a case report of cutaneous neoplasia in a special area RESUMO O carcinoma basocelular (CBC) é o câncer de pele mais comum.¹ Entre os fatores de risco para seu desenvolvimento estão a exposição a radiações ionizantes e não ionizantes, alguns produtos químicos e cicatrizes prévias.² Porém, o fator mais importante é a exposição à radiação ultravioleta, o que explica a maior incidência dessa neoplasia em áreas fotoexpostas. O CBC em áreas não expostas é incomum. O objetivo deste relato é descrever um caso de CBC recorrente na vulva, demonstrar a importância do exame dermatológico em áreas incomuns e relatar a aplicação da cirurgia micrográfica de Mohs.
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