Exercise-induced ST segment elevation in infarct-related leads has a high specificity and acceptable sensitivity for detection of residual viability within the infarcted area.
To investigate the effect of diabetes on stroke after myocardial infarction (MI), we studied consecutive MI patients admitted to the coronary-care unit prospectively, and compared diabetics with non-diabetics. Seven per cent (11/148) of diabetics and 3% (8/297) of non-diabetics had a stroke within 1 month after MI (P = 0.020). Previous stroke and hypertension were significant risk factors for stroke after MI in diabetics, but there were no significant risk factors in non-diabetics. Hypertension was more frequent in diabetics with (12/14; 86%) than in diabetics without (63/134; 47%) a previous stroke (P less than 0.025). Severe hypotension was more frequent in diabetics (9/11) than in non-diabetics with stroke after MI (0/8) (P = 0.002). We conclude that hypertension is a risk factor for stroke after MI in diabetics, and that may be at risk for hypotensive stroke after MI. Stroke after MI may be more frequent in diabetics than in non-diabetics.
In a population known to have a high prevalence of diabetes (DM), we undertook a prospective study of the effect of risk factors for atherothrombotic stroke on stroke following acute myocardial infarction (AMI). In a multivariate linear logistic regression analysis, age and prior stroke (PCVA) contributed significantly to the risk of stroke after AMI. Patients with both hypertension (HTN) and DM (HTN+DM) were more likely to develop stroke than patients with one or none of these factors (p = 0.045). Age, PCVA and HTN+DM are risk factors for stroke after AMI. There appears to be a synergistic effect between HTN and DM on the incidence of stroke after AMI.
Despite a generalized belief that women are protected from cardiovascular disease, this remains the leading cause of death in women. This review focuses on differences in symptomatology, diagnostic modalities and therapeutic strategies in women with regard to cardiovascular disease.
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