Recent research suggests intimate partner violence (IPV) is commonly experienced by many people living with HIV/AIDS, which can complicate their care. We introduce a novel approach to screening for history of violence among 102 women of color living with HIV and receiving care at an outpatient public health clinic. Using a composite measure composed of data from a variety of screening tools, we were able to determine that 70.6% of the women had a history of violence using the composite measure, and that 43% screened positive using multiple screening tools. Although overall viral load suppression rate was high at 81.4%, women with a history of violence were less likely to be virally suppressed when compared to those without such a history (76.4% versus 93.3%, p<0.05). Our findings suggest using a variety of screening questions at entry and at follow-up care appointments may be key to identifying and supporting women survivors who may not disclose violence when first asked. Future research should foster further development, analysis, and use of a variety of screening tools such as those used in this study.
Almost two thirds (64.6%) of the 309 patients had a diagnosis of EDNOS based on the DSM-IV criteria. By contrast, only four patients had a diagnosis of unspecified feeding or eating disorder based on the DSM-5 criteria. These data demonstrate that the goal of providing more specific diagnoses for patients with eating disorders has been accomplished very successfully by the new DSM-5 criteria.
Purpose: Two independent studies of rural African American youths were used to test the moderation effect a novel haplotype in the corticotropin-releasing hormone receptor 1 gene (CRHR1) on the link between life stress and the change of depression over 4 years. Methods: 16-year-old (N ¼ 502) and 18-year-old (N ¼ 347) African American youths were randomly selected from rural Georgia as a part of two 4-year longitudinal studies (SAAFT and AIM). Negative life event and depression symptoms were collected over 4 years. Genetic data were also collected along with the survey data. Haplotype analysis were performed on 10 SNPs of the CRHR1 gene and a GC haplotype was identified as a protective factor of youth depression. A latent growth model was performed to test whether the GC haplotype moderates the link between wave 1 negative life event and change (slope) of youth depression across 4 years. We replicated the analysis with the two independent data sets. All the analyses were performed in MPLUS 6.0. Results: A CRHR1 haplotype X negative life event (GXE) interaction significantly predicted the slope of youth depression in the latent growth model (b ¼ -.03, p < .05 for SAAFT and b ¼ -.05, p < .05 for AIM) With exposure to high level negative life event at wave 1 (1 SD above mean), youths who do not carry a CG copy in the CRHR1 haplotype showed stable and high depression across time while those who carry a least one CG copy showed a decreasing trend in depression. Youths who carry a CG haplotype were protected from the influence of stressful life events. Similar results were found both in SAAFT and AIM. Conclusions: The replication design strengthens the findings of the current study. Results suggest that a diathesis-stress hypothesis was supported as oppose to a susceptibility hypothesis when concerning a GXE interaction.
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