Currently, clinical determination of pathologic fracture risk in the hip is conducted using measures of defect size and shape in the stance loading condition. However, these measures often do not consider how changing lesion locations or how various loading conditions impact bone strength. The goal of this study was to determine the impact of defect location on bone strength parameters in both the sideways fall and stance-loading conditions. We recruited 20 female subjects aged 48-77 years for this study and performed MRI of the proximal femur. Using these images, we simulated 10-mm pathologic defects in greater trochanter, superior, middle, and inferior femoral head, superior, middle, and inferior femoral neck, and lateral, middle, and medial proximal diaphysis to determine the effect of defect location on change in bone strength by performing finite element analysis. We compared the effect of each osteolytic lesion on bone stiffness, strength, resilience, and toughness. For the sideways fall loading, defects in the inferior femoral head (12.21%) and in the greater trochanter (6.43%) resulted in the greatest overall reduction in bone strength. For the stance loading, defects in the mid femoral head (−7.91%) and superior femoral head (−7.82%) resulted in the greatest overall reduction in bone strength. Changes in stiffness, yield force, ultimate force, resilience, and toughness were not found to be significantly correlated between the sideways fall and stance-loading for the majority of defect locations, suggesting that calculations based on the stance-loading condition are not predictive of the change in bone strength experienced in the sideways fall condition. While stiffness was significantly related to yield force (R 2 > 0.82), overall force (R 2 > 0.59), and resilience (R 2 > 0.55), in both, the stance-loading and sideways fall conditions for most defect locations, stiffness was not significantly related to toughness. Therefore, structure-dependent measure such as stiffness may not fully explain the post-yield measures, which depend on material failure properties. The data showed that MRI-based models have the sensitivity to determine the effect of pathologic lesions on bone strength.
Volunteer managers identify challenging tasks, such as volunteer buy-in, retention, and role matching. Successful management of these tasks is influenced by how volunteers anticipate and perceive their volunteer experience. Volunteers receive and interpret messages about the drivers, rules, and expectations of giving one’s time and expertise from what they observe in the media. Television portrays how society perceives volunteering and compulsory community service. We used textual analysis to interpret portrayals of volunteering in 104 storylines on U.S. television. Television characters portrayed as volunteers were primarily motivated by civic duty, committed on a short-term basis, and had a positive experience. The volunteer manager was often absent. The intended beneficiary need not be present because the volunteer was the ultimate beneficiary. The storylines on TV excluded important components of the volunteer experience, meaning volunteer managers may need to take steps to mitigate problems associated with unrealized expectations of the TV binge-watching volunteers.
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