Exfoliation of lamellar materials into their corresponding layers represented a breakthrough, due to the outstanding properties arising from the nanometric thickness confinement. Among the cleavage techniques, liquid-phase exfoliation is now on the rise because it is scalable and leads to easy-to-manipulate colloids. However, all appropriate exfoliating solvents exhibit strong polarity, which restrains a lot the scope of feasible functionalization or processing of the resulting flakes. Here we propose to extend this scope, demonstrating that nanosheets exfoliated in a polar medium can be properly dispersed in a non-polar solvent. To that purpose, we prepared suspensions of molybdenum disulfide flakes in isopropanol/water and developed a phase transfer of the nanosheets to chloroform via precipitation and redispersion/centrifugation sequences, without any assisting surfactant. The colloidal stability of the nanosheets in chloroform was found to be governed by their lateral dimensions and, although lower than in polar media, proved to be high enough to open the way to subsequent functionalization or processing of the flakes in non-polar medium.

The ability of amyloid-␤ peptide (A␤) to disrupt membrane integrity and cellular homeostasis is believed to be central to Alzheimer's disease pathology. A␤ is reported to have various impacts on the lipid bilayer, but a clearer picture of A␤ influence on membranes is required. Here, we use atomic force and transmission electron microscopies to image the impact of different isolated A␤ assembly types on lipid bilayers. We show that only oligomeric A␤ can profoundly disrupt the bilayer, visualized as widespread lipid extraction and subsequent deposition, which can be likened to an effect expected from the action of a detergent. We further show that A␤ oligomers cause widespread curvature and discontinuities within lipid vesicle membranes. In contrast,thisdetergent-likeeffectwasnotobservedforA␤monomers and fibers, although A␤ fibers did laterally associate and embed into the upper leaflet of the bilayer. The marked impact of A␤ oligomers on membrane integrity identified here reveals a mechanism by which these oligomers may be cytotoxic.

We investigate in detail the optical, electrochemical, structural and electrical properties of polythiophenes with increasing content of polar side chains.

A series of semiconducting small molecules with bithiophene or bis‐3,4‐ethylenedioxythiophene cores are designed and synthesized. The molecules display stable reversible oxidation in solution and can be reversibly oxidized in the solid state with aqueous electrolyte when functionalized with polar triethylene glycol side chains. Evidence of promising ion injection properties observed with cyclic voltammetry is complemented by strong electrochromism probed by spectroelectrochemistry. Blending these molecules with high molecular weight polyethylene oxide (PEO) is found to improve both ion injection and thin film stability. The molecules and their corresponding PEO blends are investigated as active layers in organic electrochemical transistors (OECTs). For the most promising molecule:polymer blend (P4E4:PEO), p‐type accumulation mode OECTs with µA drain currents, μS peak transconductances, and a µC* figure‐of‐merit value of 0.81 F V−1 cm−1 s−1 are obtained.