An increasing number of outbreaks due to resistant non-albicans Candida species have been reported worldwide. Between 2014 and 2016, Candida isolates causing invasive candidiasis were recovered in a Mexican hospital. Isolates were identified to species level and antifungal susceptibility was determined. In the time period studied, 74 invasive candidiasis cases were identified, with 38% (28/74) caused by Candida parapsilosis, out of which 54% (15/28) were fluconazole resistant. The ERG11 gene was sequenced for 12 recoverable fluconazole-resistant C. parapsilosis isolates and SNPs identified. The 12 isolates had one common silent point mutation in ERG11 (T591C) and seven isolates had an additional (A395T) mutation, which corresponded to Y132F. Four of the isolates carrying this mutation were closely related within the same cluster by microsatellite typing. This is the first report of an invasive candidiasis outbreak in Mexico due to azole-resistant C. parapsilosis associated with the Y132F substitution.

This publication highlights the effect of CO treatments on both calcined and reduced catalysts by using novel in situ techniques to track particle transformations, which are so vital to catalyst performance and activity. Cobalt carbide formation has been shown to occur readily with CO treatments on metallic cobalt particles, and in this study we have used in situ XRD and temperature‐programmed reduction (TPR) techniques to track the evolution of the carbide. We were able to show a dependence on CO partial pressures and the formation of a single hexagonal phase of cobalt as a result of the carbide step. The stability of cobalt carbide was studied and its reduction in hydrogen to cobalt metal was observed. CO was also used as the reducing gas and by using TPR and in situ XRD we were able to demonstrate the reduction of cobalt oxide (Co3O4) to cobalt carbide (Co2C) via both oxide (CoO) and metal (Co) intermediates.

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While Fischer‐Tropsch (FT) provides a commercially operated route to long‐chain alkanes for fuels, little is reported showing realistic routes to long‐chain linear alcohols and linear olefins. Linear olefins and alcohols have significant commercial value for lubricants, plasticizers, detergents and base chemicals, and in this contribution, FT has gained considerable recent attention due to the potential for bio or waste feeds for fuels and chemicals, while here we demonstrate that controlling the promotion of a cobalt catalyst with manganese can lead to major shifts in selectivity towards high value chemicals. In this contribution, we demonstrate the unusual effect of adjusting manganese from 0–10 % for making long‐chain linear alcohols and olefins using industrially relevant conditions. A full evaluation of the catalysts is provided to demonstrate catalyst changes as a result of increased promotion that gives rise to this effect. Advanced wax‐product analysis is shown to demonstrate the changes in selectivity. Temperature‐programmed reduction, transmission electron microscopy elemental mapping and in situ x‐ray diffraction show the formation of CoxMnyO4 species on titania during synthesis, with cobalt‐manganese alloys after reduction, while 2D gas chromatography (GCxGC) and 1H nmR were used to analyse the FT wax product with over 50 % alcohols at long carbon numbers.