We demonstrate a solution-based fabrication of centimeter-size free-standing films assembled from organic nanocrystals based on common organic dyes (perylene diimides, PDIs). These nanostructured films exhibit good mechanical stability, and thermal robustness superior to most plastics, retaining the crystalline microstructure and macroscopic shape upon heating up to 250-300 °C. The films show nonlinear optical response and can be used as ultrafiltration membranes. The macroscopic functional materials based on small molecules can be alternative or complementary to materials based on macromolecules.
Quilter often said he loved Poetry more than music. The poems he set to music would form an anthology of some of the choicest lyrics in the English language, while a collection of those poems which he loved but considered unsuitable for music, would give us an insight into his kind and gentle nature. Evenings spent in his company were a sheer delight. He had a great sense of humour, exquisite taste, and he delighted in surrounding himself with beautiful things. Helpful to young artists and friends, his generosity was of a most uncommon kind.
Background: Vaccine-derived poliovirus (VDPV) remains a significant barrier to global poliomyelitis eradication. Following 18 years of polio-free status, an epidemic of circulating VDPV type 1 (cVDPV1) occurred in Papua New Guinea (PNG) in 2018. We describe the epidemiology of the 2018 cVDPV1 epidemic in PNG, and identify risk factors which may aid future policy and control efforts.Methods: Data pertaining to the 2018 PNG epidemic were extracted from EPIWATCH and supplemented with data from other sources, such as the World Health Organization (WHO), and published literature. Descriptive analyses were undertaken, and key risk factors identified.Results: 26 cases of cVDPV1 were confirmed throughout the duration of the epidemic (April to October 2018) in nine provinces. Of the 26 cases, 19 (73%) were males and 7 (27%) were females, and most of the cases (73%) occurred in children under the age of five. Population immunization coverage of three doses of oral polio vaccine (OPV3) was found to fluctuate between 60-80% between 2000 and 2018. Nonpolio Acute Flaccid Paralysis (NPAFP) surveillance rates were also found to be suboptimal over this period.Conclusions: A combination of low routine immunization coverage, lacking supplementary immunization activities, and ineffective surveillance systems, in the context of a struggling health system, culminated in this epidemic. To prevent future poliomyelitis epidemics in PNG, emphasis must be placed on supporting the health system to maintain high vaccination coverage, in conjunction with robust and effective surveillance systems.
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