Extranodal lymphomas which present in the nasal cavity and/or the paranasal sinuses are rare. Thirty-eight patients with disease that was clinically limited to the head and neck (Ann Arbor Stages IE-IIE) were admitted between 1947 and 1983. Twenty-eight patients were treated with radiotherapy alone and 10 received combination chemotherapy in addition. The overall 5-year survival figure was 56%. The corresponding result for Stage IE was 67%. No patient with Stage IIE disease survived 5 years. Extent of the extranodal disease also influenced results for Stage IE patients who were treated with radiotherapy only. When the extranodal disease was staged using the American Joint Committee TNM system, the 5-year disease-free survival for T1 and T2 patients was 78% as compared with 19% for patients with T3 and T4 disease. The addition of combination chemotherapy improved results for patients with T3 and T4 lesions. Cancer 56:814-819, 1985. YMPHOMAS originating in the nasal cavity and/or L the paranasal sinuses are very uncommon. Gall and Mallory' reported only 2 cases from a series of 6 18 malignant lymphomas (0.3%) and Freeman et al.' cited 33 cases in a series of 1467 non-Hodglun's lymphomas (2%). Wong er al.' in a previous study of 128 patients with extranodal lymphomas of the head and neck found 16 (1 3%) cases. The incidence of lymphoma in relation to other malignant tumors of the nasal cavity and associated sinuses is also low representing less than Also, lymphomas presenting in this region are almost exclusively non-Hodgkin's lymphomas. The diffuse large cell variety is by far the most common.