No abstract

An otitis media with effusion model in human temporal bones with two laser vibrometers was created in this study. By measuring the displacement of the stapes from the medial side of the footplate, the transfer function of the middle ear, which is defined as the displacement transmission ratio (DTR) of the tympanic membrane to footplate, was derived under different middle ear pressure and fluid in the cavity with a correction factor for cochlear load. The results suggest that the DTR increases with increasing frequency up to 4k Hz when the middle ear pressure was changing from 0 to 20 or -20 cm H20 (e.g., +/-196 daPa) and fluid level was increasing from 0 to a full middle ear cavity. The positive and negative pressures show different effects on the DTR. The effect of fluid on DTR varies between three frequency ranges: f < 1k, between 1k and 4k, and f > 4k Hz. These findings show how the efficiency of the middle ear system for sound transmission changes during the presence of fluid in the cavity and variations of middle ear pressure.

Stapes and TM displacement transfer functions were determined using dual interferometry, provided accurate amplitude and phase relationships from stapes footplate, IS joint, and TM, with new data from drained and normal cochlea.

The middle ear as a levered vibrating system for sound transmission from the external to the inner ear is affected by changes in ossicular chain mass. Mass loading of the ossicles may impair ossicular dynamics and sound transmission to the inner ear. It is incumbent on otologic surgeons and researchers of middle ear mechanics to consider the mass loading effect on middle ear function in clinical and physiological applications. The residual hearing and frequency response can change after surgery or implantation of middle ear prostheses. We conducted experiments on mass loading effects on the middle ear transfer functions by using laser Doppler interferometry and a human temporal bone model. Two implant mass loading conditions were tested on 17 fresh or fresh-frozen temporal bones and compared with the unloaded condition for the frequencies 250 to 8,000 Hz. The results show that the linearity of the middle ear function did not change, although displacement of the stapes footplate decreased after the increased masses were placed on the incudostapedial joint. The greater the mass of the implant, the less displacement was measured at the stapes footplate. We conclude that there is a quantitative limit to increased mass on the ossicular chain above which the mass will remarkably impair hearing thresholds.

A three-dimensional finite element ͑FE͒ model of human ear with structures of the external ear canal, middle ear, and cochlea has been developed recently. In this paper, the FE model was used to predict the effect of tympanic membrane ͑TM͒ perforations on sound transmission through the middle ear. Two perforations were made in the posterior-inferior quadrant and inferior site of the TM in the model with areas of 1.33 and 0.82 mm 2 , respectively. These perforations were also created in human temporal bones with the same size and location. The vibrations of the TM ͑umbo͒ and stapes footplate were calculated from the model and measured from the temporal bones using laser Doppler vibrometers. The sound pressure in the middle ear cavity was derived from the model and measured from the bones. The results demonstrate that the TM perforations can be simulated in the FE model with geometrical visualization. The FE model provides reasonable predictions on effects of perforation size and location on middle ear transfer function. The middle ear structure-function relationship can be revealed with multi-field coupled FE analysis.