This study evaluates the effects of combinations of pyrethroids and neonicotinoids on the control of stink bugs at different stages of soybean crop development. The experiment was set up in a factorial randomized block design (4×6: 4 treatments and 6 stages) with 4 repetitions. The following treatments were tested during the V6/V7, R2, R4, R5.1, R5.5 and R 6 phenological stages: 1 – control (no application), 2 – thiamethoxam + λ-cyhalothrin, 3 – acetamiprid + α-cypermethrin, and 4 – dinotefuran + α-cypermethrin. Infestation, number of damaged seeds, number of pods, number of pods per plant, and yield (kg/ha) were evaluated. Stink bug infestations were smaller when applications commenced during the vegetative stages (V6-V8). Pod numbers and yields were highest in the dinotefuran + α-cypermethrin treatment with applications from V6/V8 to R4. The active ingredients dinotefuran + α-cypermethrin reduced stink bug populations and increased yields and could therefore be considered in integrated pest management (IPM) programs for soybean crops.