Aims: Malnutrition among children, especially stunting is a public health problem in Cameroon. This study assesses the impact of zinc supplementation of children and nutrition education of mothers on the nutritional status of the children in the Bangang rural community. Study Design: This was a descriptive and prospective study. Place and Duration of Study: The study took place in the Bangang community in the Region of West Cameroon, during the period from March to December 2015. Methodology: The children aged 6 to 48 months and mothers aged 20 to 34 years were selected after the baseline survey and enrolled. Dietary surveys were used to evaluate the frequency of foods consumed by 150 children. Zinc supplementation group of children (ZSG, n= 25) received 10 mg of zinc sulfate tablets per day for 14 days and control group (CG, n=25) was formed by children whose mothers received nutrition counseling. The nutrition education sessions organized into 4 modules were conducted quarterly for 9 months on a sample of 100 mothers. After interventions, impact of zinc supplementation and maternal education was assessed by determining height for age and weight for age indices, and biochemistry parameters. Results: The results showed that zincemia of ZSG varied significantly (P = .0001) and not significantly (P = .23) for CG. After nutrition education, dietary diversity was improved; reduction of chronic malnutrition (10.9%) and increasing number of children with good nutritional status (6.6%) were observed. Increased for phosphoremia (3.6 ± 2.4 to 5.7 ± 1.8 mg/dl; P = .001) and albuminemia (34.8 ± 15.5 to 46.9 ± 8.9 g/l; P = .002) were significant which was not the case of calcemia, zincemia, magnesemia and serum iron. Conclusion: This study showed positive impact of zinc supplementation and maternal education on the nutritional status of children.