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Introduction. Anti-TNF treatment has transformed the treatment of chronic inflammatory rheumatism. Although the therapy can be highly effective, anti-TNF drugs are associated with an increased risk of tuberculosis, especially extra-pulmonary tuberculosis. Laryngeal tuberculosis is rare and its symptoms are not specific. Laryngeal tuberculosis is often secondary to another localization, particularly pulmonary. In the use of anti-TNF therapy, its development is unusual. Case report. We report a case of bifocal tuberculosis: laryngeal and pulmonary tuberculosis revealed by laryngeal involvement in a patient aged 41 years with axial spondylarthritis treated with Adalimumab. Conclusion. This presentation highlights the importance to consider the rare possibility of laryngeal tuberculosis in the presence of atypical otorhinolaryngologic signs under anti-TNF therapy and underlines the importance of looking for other tuberculosis involvement.

Rhinolithiasis are foreign bodies that develop in the nasal cavities according to a poorly understood physicochemical mechanism. At first, they are asymptomatic, but once they are large, they give nasal obstruction with all the possible complications that can make it more difficult surgical management. we are going to present the case of a patient presenting with a rhinolithiasis discovered following a chronic nasal obstruction and whose endoscopy allowed the diagnosis and the extraction.

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