La incorporación al ámbito universitario conlleva estrés. El desarrollo de las habilidades emocionales puede ayudar a los jóvenes a hacer frente a los nuevos retos académicos y mejorar su rendimiento y bienestar personal. El objetivo del presente trabajo fue estudiar la relación entre inteligencia emocional, empatía y bienestar subjetivo. Los participantes fueron 122 estudiantes universitarios entre 18 y 32 años (M=20.93; DT=2.55; 83.60% mujeres) que completaron los cuestionarios: Trait Meta-Mood Scale-24 (TMMS-24), Basic Empathy Scale (BES), Satisfaction with Life Scale (SWLS) y Scale of Positive and Negative Experiences (SPANE). Se realizaron análisis descriptivos y de regresión lineal múltiple. Los resultados indicaron una influencia de las habilidades emocionales sobre el bienestar subjetivo. La empatía cognitiva, la atención y la claridad explicaron el 30% de la varianza de la satisfacción con la vida (R2=.30). La edad y la reparación emocional predijeron el 17% de la varianza de los afectos positivos (R2=.17). El sexo, la empatía cognitiva, la claridad, la atención y la reparación emocional explicaron el 28% de la varianza de los afectos negativos (R2=.28). Un exceso de atención puede influir negativamente en el bienestar, mientras que la claridad y la reparación podrían considerarse predictores positivos del bienestar subjetivo.

Background: Hospital malnutrition is an increasingly prevalent situation, which involves both an increase in health costs, a decrease in the life quality of those who suffer from it, and greater morbimortality. Nutritional screening is essential to detect malnutrition early and avoid these complications.Methods: NRS-2002 was performed on all patients admitted to the oncohaematology service, followed by the complete nutritional assessment (VN) to check its validity, which is repeated weekly to determine the degree of malnutrition during the hospital stay. Data were summarized using mean (standard deviation) and median (1st, 3rd quartile) for numerical variables, and absolute frequency (relative) for qualitative variables. To measure agreement between the two diagnoses, Cohen's Kappa was calculated for each visit. The level of association between the variables was measured using the Goodman and Kruskal measure.Results: 573 patients were admitted to the oncohaematology service, of which: 34.4% malnutrition, 44.7% risk of malnutrition and 20.9% good nutritional condition, on admission to hospital according to the NRS-2002. In patients admitted for more than a week, NRS-2002 was performed weekly and found that, upon discharge, they suffered: 34.4% malnutrition, 50.8% risk of malnutrition and 14.76% good nutritional status; also 12.3% worsen their nutritional status, 68.9% maintain it and only 18.9% improve it. 78.8% of patients with longer admissions require a VN. Conclusions:Our results suggest that the NRS-2002 is a simple and effective method for early malnutrition detection. It's important a nutritional monitoring during the hospitalization period, because the patients are susceptible to worsening of their nutritional status.

The condensed form of neural extracellular matrix (ECM), perineuronal nets (PNNs), is predominantly associated with parvalbumin-expressing (PV+) interneurons in the cortex and hippocampus. PNNs are enriched in several lecticans, including neurocan (Ncan). A polymorphism in the human Ncan gene has been associated with alterations in hippocampus-dependent memory function, variation of prefrontal cortex structure, and a higher risk for schizophrenia or bipolar disorder. Ncan knockout (KO) mice show related behavioral abnormalities, such as hyperactivity. Here we focused on studying how dysregulation of Ncan specifically in the mPFC may affect cognitive and synaptic functions. Intracortical adeno-associated virus (AAV) delivery was used to express shRNA against Ncan. Analysis of PNNs in Ncan shRNA-injected mice revealed a reduction in PNNs labelling by Wisteria floribunda agglutinin (WFA) around PV+ interneurons. Reduced Ncan expression resulted in a loss of the mPFC-dependent temporal order recognition and impairment of reversal spatial learning in a labyrinth (dry maze) task. As a potential synaptic substrate of these cognitive abnormalities, we report a robust reduction in the perisomatic GABAergic innervation of PV+ cells in Ncan KO and Ncan shRNA-injected mice. We also observed an increase in the density of vGLUT1-immunopositive synaptic puncta in the neuropil of Ncan shRNA-injected mice, which was, however, compensated in Ncan KO mice. Thus, our findings highlight a functional role of Ncan in supporting perisomatic GABAergic inhibition, temporal order recognition memory and cognitive flexibility, as one of the important cognitive resources depleted in neuropsychiatric disorders.