In this paper, we present a new method for developing a class of nested multiscale models for directly transmitted infectious disease systems that integrates within-host scale and between-host scale using community pathogen load (CPL) as a new public health measure of a community’s level of infectiousness and as an indicator of the effectiveness of health interventions. The approach develops a multiscale modeling science base for directly transmitted infectious disease systems (where the inside-host environment’s biological entities such as cells, tissues, organs, body fluids, whole body are the reservoir of infective pathogen in the community) that is comparable to an existing multiscale modeling science base for environmentally transmitted infectious diseases (where the outside-host geographical environment’s physical entities such as soil, air, formites/contact surfaces, food and water are the reservoir of infective pathogen in the community) where pathogen load in the environment is explicitly incorporated into the model. This is achieved by assuming that infected hosts in the community are homogeneous and unevenly distributed microbial habitats. We illustrate the utility of this multiscale modeling methodology by evaluating the comparative effectiveness of HIV/AIDS preventive and treatment interventions as a case study.
Word embeddings provide quantitative representations of word semantics and the associations between word meanings in text data, including in large repositories in media and social media archives. This article introduces social psychologists to word embedding research via a consideration of bias analysis, a topic of central concern in the discipline.We explain how word embeddings are constructed and how they can be used to measure bias along bipolar dimensions that are comparable to semantic differential scales. We review recent studies that show how familiar social biases can be detected in embeddings and how these change over time and in conjunction with real-world discriminatory practices.The evidence suggests that embeddings yield valid and reliable estimates of bias and that they can identify subtle biases that may not be communicated explicitly. We argue that word embedding research can extend scholarship on prejudice and stereotyping, providing measures of the bias environment of human thought and action.
Social science has traditionally measured opinions using surveys, recording responses on simplified bipolar scales. However, everyday opinions are expressed in more complex and nuanced language than is captured in survey items; they are formed in the context of debate as speakers take sides with and against other opinions. We propose a new approach to study opinion, based on the idea of ordering speakers in a spatial representation according to the linguistic similarity of their contributions to a debate. Such “speaker landscapes” can be constructed quantitatively from large text corpora by exploiting the ability of machine learning to find patterns in text. Using this tool, we investigate opinion in two South African case studies: the twitter debate around the arrest and imprisonment of former president Jacob Zuma, and opinion statements quoted in the news media about the controversial issue of land reform. We find that speaker landscapes expose both social and linguistic dimensions of opinion and identify the characteristic terms, feelings and topics associated with clusters of opinion.
This article presents results from a study that developed and tested a word embedding trained on a dataset of South African news articles. A word embedding is an algorithm-generated word representation that can be used to analyse the corpus of words that the embedding is trained on. The embedding on which this article is based was generated using the Word2Vec algorithm, which was trained on a dataset of 1.3 million African news articles published between January 2018 and March 2021, containing a vocabulary of approximately 124,000 unique words. The efficacy of this Word2Vec South African news embedding was then tested, and compared to the efficacy provided by the globally used GloVe algorithm. The testing of the local Word2Vec embedding showed that it performed well, with similar efficacy to that provided by GloVe. The South African news word embedding generated by this study is freely available for public use.
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