Highlights d Aptamers can be used to reversibly label and purify cells via FACS or MACS d EGFR aptamer-magnetic bead MACS isolates EGFR+ cells out of complex cell mixtures d An oligonucleotide ''antidote'' strips off aptamers to recover label-free cells d EGFR aptamer FACS sorting and antidote removal restores native receptor function
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