Results of intraventricular resynchronization in patients with severe cardiac failure Background: Intraventricular resynchronization with pacemakers is a promising therapy for patients with refractory cardiac failure and intraventricular conductions delay. However its long term effects are not well known. Aim: To report the results of this therapy in patients with cardiac failure. Patients and methods: Fourteen patients (11 male), whose mean age was 68 years, with a severe and refractory cardiac failure, have been treated in our unit using intraventricular resynchronization with pacemakers. Eight had a coronary heart disease and six a dilated myocardiopathy. The pacemaker was implanted transvenously, with conventional stimulation in atrium and right ventricle. The left ventricle was stimulated through an epicardial vein, accessed through the coronary sinus. Results: In one patient the high thresholds did not allow a left ventricular stimulation. In the other 13 patients, a clinical improvement was observed in 11 (85%), that has been sustained for a mean of 8.2 months. The ejection fraction improved form 23.5 to 32.4% (p <0.001), the 6 min walking test improved from 347 to 437 m (p=0.003) and the functional capacity changes from 3.3 to 2.7 (p <0.001). Three patients died during follow up. One was the patient in whom the stimulation failed and two had a sudden death. No complications of the procedure were observed. Conclusions: In this series, intraventricular resynchronization with pacemakers was effective in 11 of 13 patients, improving functional capacity and ejection fraction. Sudden death could be avoided adding a defibrillator to the pacemaker system (

Pleomorphic adenoma (PA) is the most common neoplasm encountered in major and minor salivary glands. Intraorally, it is most frequently developed in the palatal glands. Histologically, it is characterized by a diverse architecture comprised of epithelial stromal elements mixed with mucoid, myxoid, or chondroid fibrohyaline. A PA does not generally present gender bias and can occur at any age with the same clinical behavior. It is usually a round, slow-growing, painless tumor, which is firm upon palpation. We reported two cases of adult patients who were treated using transoral resection at San Juan de Dios Hospital in La Serena. Keywords: Pleomorphic Adenoma, Salivary Glands, Tumor.Adenoma pleomorfo palatino: Reporte de 2 casos y revisión de la literatura.Abstract: El Adenoma Pleomorfo es la neoplasia más común de las glándulas salivales mayores y menores. Intraoralmente las glándulas del paladar son las más afectadas. Histológicamente se caracteriza por una arquitectura variada que comprende elementos epiteliales mezclados con estroma mucoide, mixoide, fibrohialino o condroide, Los AP no suelen presentar predisposición por sexos, pudiendo aparecer a cualquier edad, con el mismo comportamiento clínico. Se presentan habitualmente como una tumoración redondeada de crecimiento lento, indolora y firme a la palpación. Presentamos dos casos de pacientes adultos, quienes fueron tratados mediante resección transoral en el hospital de la Serena.

Resumen: El Pilomatrixoma o epitelioma calcificado de Malherbe es un tumor benigno derivado de los folículos pilosos. Afecta con más frecuencia a niños y adultos jóvenes. Ellos son nódulos dérmicos o subcutáneos que se presentan normalmente en forma asintomática, solitarios, con una consistencia firme o dura y no adheridos a planos profundos. Reportamos un caso de una niña con un pilomatrixoma en la región preauricular.