Outbreak of persistent cutaneous abscesses due to Mycobacterium chelonae after mesotherapy sessions, Lima, Peru Surto de abscessos cutâneos persistentes por Mycobacterium chelonae pós-mesoterapia, Lima, Peru ABSTRACT Outbreaks of rapidly growing mycobacteria have been occasionally described. The article reports an outbreak of cutaneous abscesses due to Mycobacterium chelonae following mesotherapy in Lima, Peru. From December 2004 through January 2005, 35 subjects who had participated in mesotherapy training sessions presented with persistent cutaneous abscesses. Thirteen (37%) of these suspected cases consented to underwent clinical examination. Skin punch-biopsies were collected from suspicious lesions and substances injected during mesotherapy were analyzed. Suspected cases were mainly young women and lesions included subcutaneous nodules, abscesses and ulcers. Mycobacterium chelonae was isolated from four patients and from a procaine vial. In conclusion, it is important to consider mesotherapy as a potential source of rapidly growing mycobacteria infections. Although rapidly growing mycobacteria (RGM) are ubiquitous, diseases caused by these atypical bacteria are relatively uncommon. 1 Among RGM, Mycobacterium chelonae is particularly prominent. Clinical diseases caused by this agent include cutaneous infections ranging from localized cellulitis to osteomyelitis. The precise burden of disease caused by this microorganism is unknown and most available information comes from occasional case reports. Cutaneous infections caused by RGM, including M. chelonae, have been associated with penetrating cutaneous trauma. Common procedures related to RGM-related infections included injections, liposuction, acupuncture and, more rarely, catheter insertions. 1

Abstract. Lobomycosis is a chronic subcutaneous mycosis for which no standard treatment is available to date. We describe a patient in Peru with lobomycosis on the left earlobe that was successfully treated with posaconazole for 27 months. No evidence of recurrence was observed after five years of follow-up.Lobomycosis (lacaziosis) is a chronic subcutaneous disease caused by the fungus Lacazia loboi, which is reported mainly in Central and South America, mostly from Brazil and Colombia.

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Objetivo: Determinar la frecuencia de demodicidosis y sus características clínicas en pacientes con rosácea. Materiales y métodos: Estudio de casos y controles en 42 pacientes con rosácea y 42 controles para describir la presencia y densidad de D. folliculorum. El estudio se realizó en el Hospital Nacional Cayetano Heredia entre marzo y setiembre del 2004, utilizándose la técnica de Tello. Resultados: Demodex folliculorum fue encontrado en los 42 pacientes con rosácea (100%) y en 13 (31,0%) del grupo control, (p= 0,000). La exposición a gatos, la crianza de roedores y cerdos, la seborrea y el uso de corticoides tópicos fueron mas frecuentes en los pacientes con rosácea. Conclusiones: La presencia de Demodex folliculorum fue más frecuente en los pacientes con rosácea.

It has been considered that the behavior of tumors is consistent with the concept that tumor growth is angiogenesis dependent. However, additionally to the newly formed vessels other patterns of tumor capillaries have been described. Information concerning the ultrastructure of tumor blood vessels has been obtained mostly from experimental models. With regard to human tumors, since no systematic ultrastructural studies are available on the gastric tumor microvasculature, the aim of the present work was to characterize the vascular architecture of this type of tumor.Surgically resected specimens were obtained in tumors from five patients (three males and two females) between 45 to 66 years of age (mean, 56.2 years), with a histopathological diagnosis of moderately differentiated gastric adenocarcinoma. Immediately after resection, tissue samples taken from areas of tumor center were processed by routine transmission electron microscopy techniques and observed in a Hitachi H-500 EM.The microvasculature within gastric adenocarcinomas was characterized by newly formed capillaries with proliferative endothelial cytoplasm (Fig. 1).