Physical activity is an effective method for managing depressive symptoms, and web-based interventions may be an effective tool for promoting physical activity within this population. People with depressive symptoms may experience condition-specific facilitators and barriers to be considered when developing physical activity interventions. This study provides insight into web-based physical activity intervention preferences and physical activity motivation of people with depressive symptoms. This study was part of a larger trial of a web-based physical activity intervention for people with depressive symptoms. Thematic analysis of participants ' (N = 20) written responses to open-ended survey questions was conducted. Preferences for web-based intervention features included social forums, self-monitoring, suggestions for types of physical activity in different circumstances and information targeted to people with depressive symptoms. When discussing physical activity motivation instrumental beliefs (i.e., beliefs of the benefits and cost of physical activity) and controllability (i.e., whether the behaviour is under their control) were discussed. Additionally, people reported condition-specific barriers of physical activity such as depressive symptoms of apathy, worthlessness, and pain. Further research is needed to test the effectiveness of web-based physical activity interventions targeting people with depressive symptoms, which incorporates these findings.
Finding new candidate solvents that can work as replacers for banned solvents, or that could be an improvement to existing solvents, is a time-consuming procedure. It is important to know how solvent structure affects interactions with active ingredients and how it will affect the performance in the application. To fully understand the interactions between solvents and solutes, there is a need to understand the types of interactions that are involved in such systems. This article discusses polar interaction between solvents and solutes and presents the methods that monitor polarity. Improved methods to monitor solute solubility and water solubility are also presented. Two classes of solvents are used as examples, namely, N,N-dimethyl alkaneamides and N-alkyl, N-methyl formamides. Tebuconazole is used as a model solute. The solubility of tebuconazole in the mentioned solvents as well as formulation stability is related to fundamental interaction parameters. It is clear from the analysis that there exists a correlation between the β-parameter (electron donating properties) and the solubility of tebuconazole for amide solvents. It can also be seen that the two classes of solvents investigated in this study interact to a different extent with water (i.e. both the solubility of solvent in water and the solubility of water in the solvent). From the results, it is also clear that the N-decyl, N-methyl formamide is the best suited solvent to obtain stable formulations and emulsions at low temperature for high concentrations of tebuconazole.
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