A new questionnaire is now available in French. A large body of data is currently being gathered in view of comparing occupations and types of firms using this new instrument.

The purpose of this study was to validate the French version of the Copenhagen Psychosocial Questionnaire (COPSOQ). The COPSOQ is used to assess psychosocial risk factors at work. The current French version comprises 46 items grouped in 24 scales and referring to six dimensions. The questionnaire was administered to 3,166 employees of a large French company based in ten cities of the Paris region and the provinces. The psychometric analyses (internal consistency analysis, exploratory and confirmatory factor analysis and concurrent validity analysis) were satisfactory and demonstrated the validity of the French version of the COPSOQ. Large amounts of data are currently being collected with a view to making comparisons between occupations and between different types of companies.

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IntroductionPediatric oncological patients undergoing radiotherapy require immobilization.ObjectivesThis study investigated the drugs administered and vital signs of these patients.MethodsOur study included 38 patients with mean age 29.40 ± 3.94 months, weight mean 14.64 ± 0.55 kg, height 90.47 ± 14.71 cm undergoing anesthesia for radiotherapy immobilization purpose.ResultsAll patients received sevoflurane 8% for induction and anesthesia maintenance and procedure period was 32.62 ± 2.41 minutes.Measured vital signs before anesthesia were: systolic arterial pressure 101.38 ± 2.05, diastolic arterial pressure 53.28 ± 1.80, heart rate 116.14 ± 1.80, respiratory rate 23.12 ± 0.93 and body temperature 36.01 ± 0.19.Vital signs after anesthesia were: systolic arterial pressure 96.00 ± 2.02, diastolic arterial pressure 49.20 ± 2.88, heart rate 111.63 ± 2.80, respiratory rate 23.51 ± 1.10, body temperature 36.43 ± 0.82 and oxygen saturation 97.74% ± 1.00.Emergence agitation related to the use of sevoflurane was observed in 84.21% (32) patients.Either propofol 0.5 - 4.4 mg/kg or nalbuphine 0.1-0.15 mg/kg or fentanyl 2-3.6 mg/kg controlled agitation after sevoflurane in 43.75% (14) patients.Flumazenil 0.02 mg/kg given to 5.26% (2) patients and haloperidol 1.44 mg/kg administered to 10.53% (4) and enhanced the agitation after sevoflurane.ConclusionThere were no significant difference between vital signs measured before and after anesthesia with sevoflurane. Emergence agitation due to the use of sevoflurane was observed.The use of benzodiazepines antagonist and neuroleptics should be evaluated in emergence agitation due to sevoflurane.

Sevoflurane anaesthesia is often related to emergence agitation. This study investigates the drugs administered to treat this side effect. Methods Our retrospective study included 100 oncologic paediatric patients with mean age of 33.67 ± 2.12 months, weight mean 15.22 ± 0.44 kg, height 94.68 ± 2.24 cm undergoing anaesthesia for radiotherapy immobilisation purpose. Results Sevoflurane 8% was administered to 100% of the patients for anaesthesia induction/maintenance. The number of radiotherapy session were 22.43 ± 1.01 days and the period of anaesthesia was 33.09 ± 1.81 min. Emergence agitation was observed during anaesthesia recovery in 73% patients and was treated with propofol 0.5–4.4 mg/kg (29 patients), midazolam 0.35–79 mg/kg (12 patients), nalbuphine 0.1–0.15 mg/kg (4 patients), haloperidol 1,5 mg/kg (4 patients) and fentanyl 2–3.6 mg/kg (1 patient). All these central depressant drugs controlled the emergence agitation except haloperidol which induced extrapyramidal side effect (akathisia). Conclusions Respiratory depression should be considered in sevoflurane association with central nervous system depressants. Although midazolam has flumazenil as antagonist, midazolam high dosages should be administered with caution. Neuroleptics, such as haloperidol, is not an appropriated choice for agitation considering the possibility of akathisia.