In education, the role of teachers and researchers is fundamental in the formation of committed citizens, who know their environment and make decisions for the benefit of a sustainable community. Therefore, as teachers, we must reflect, within our classes, on the current social, economic, environmental, political and cultural challenges, to prepare our students to live in a world that demands new interaction forms between all the agents of society. The main objective of the handbook Productive Systems, Territory and Sustainability T-III 2021 was to enrich the scientific literature on the topics of productive systems, territory and sustainability worldwide with full adherence to the bibliography available in various digital databases such as Web of Science, Scopus, Redalyc, among others, and printed texts from which relevant information concerning basic and applied research on the topics of the handbook was taken. The method used was multimodal given that we resorted to desk research based on quantitative techniques and field work both in Mexico and Brazil where qualitative techniques such as participant observation and the application of questionnaires were applied.