Abstract:The study investigates the effect of public health expenditure on health outcomes in Nigeria, as captured by life expectancy at birth and infant mortality rates. The result shows that public health expenditure and health outcomes have long-run equilibrium relationship. Furthermore, the results showed that an increase in public health expenditure improves life expectancy and reduces infant mortality rates. In addition, urban population and HIV prevalence rate significantly affects health outcomes, while per capita income exhibits no effect on health outcomes in Nigeria. The findings suggest that public health expenditure remains a necessary component in improving health outcomes in Nigeria.