Domestic violence against females is a very common issue In any culture, religion and ethnicity and several reasons are found to be related with it which probably cause serious health outcomes. The study was undertaken to examine the perceived stress, life satisfaction and self-esteem among females facing domestic violence. It was a correlation research study being conducted in three different centers i.e. Dar-ul-Amaan, Dastak Shelter Homes and Shaheed Benazir Bhutto Human Rights Centre for Women, Lahore Pakistan. Total sample size was 100 subjects who were selected for data collection. Purposive sampling technique was used for data collection, Perceived Stress Scale (PSS) was used for measuring mental stress level [1], Satisfaction with Life Scale (SWLS) and Rosenberg Self-esteem Scale (RSE) were used to measure a singular's emotions of self-esteem [2, 3]. The data was analyzed using the Statistical Package for Social Sciences (SPSS version 18.0) by keeping 0.05 level of significance. A total of 80 subjects were approached in the study, weak negative relationship between perceived stress and life satisfaction was r (80) =-0.385, p<0.001 and our hypothesis I was accepted; A linear regression analysis revealed that perceived stress was a significant predictor of life satisfaction (β=0.40, p= 0.008) accounting for 16% of the variance in life satisfaction. Concerning the relationship between perceived stress and self-esteem highlights an insignificant relationship was found; r(80)=0.145, p=0.705 thus Hypothesis II was rejected. Also the relationship between life satisfaction and self-esteem was not significant r(80)=0.043, p=0.199 and hypothesis III was rejected. There was considerable negative relationship observed between perceived stress and life satisfaction among females facing domestic violence, an insignificant relationship between life satisfaction and self-esteem and similarly insignificant relationship between perceived stress and self-esteem was found among females facing domestic violence.