Background
Polycystic Ovarian Syndrome (PCOS) is one of the most common endocrinopathies and metabolic disorders in women during their reproductive years. It is often associated with dyslipidemia and other risk factors of cardiovascular diseases (CVD). This study was aimed to evaluate dietary intervention effects with canola and olive oils compared to sunflower oil on lipid profile and fatty liver severity among women with PCOS.
Method
This study was a 10-week intervention including 72 women with PCOS. Patients were randomly assigned to three groups for receiving 25 g/day canola, olive, or sunflower oils for 10 weeks. The primary and secondary outcomes were to assess changes in lipid profile and in fatty liver severity, respectively.
Result
At the end of the study, 72 patients with a mean age of 29.31 were analysed. Canola oil consumption resulted in a significant reduction in serum levels of TG (P = 0.002) and TC/HDL (P = 0.021), LDL/HDL (P = 0.047), and TG/HDL (P = 0.001) ratios, however, there was no significant reduction in lipid profile following olive oil consumption. Canola (P < 0.001) and olive oils (P = 0.005) could significantly reduce the fatty liver grade. Moreover, HOMA-IR in both canola (P < 0.001) and olive (P = 0.004) groups was significantly decreased.
Conclusion
In total, compared to olive and sunflower oils, significant improvements in lipid profile, liver function, and HOMA-IR were observed following canola oil consumption in women with PCOS.
Trial registration
IR.MUI.RESEARCH.REC.1397.315. Registered 30 JUNE 2019 - Retrospectively registered, https://www.irct.ir/trial/38684
Background:As elongated styloid process is one of the causes of recurrent oropharyngeal pain and carotid nerve plexus compression called Eagle's syndrome and this length is not similar in different communities, the aim of the current study is to determine average length of styloid process by paranasal multidetector computed tomography.Materials and Methods:This is a retrospective cross-sectional study about 393 patients who underwent paranasal MDCT scan for trauma in Radiology Department without pathologic finding. Styloid length from temporal bone junction to tip of the process was measured using Workstation software. Demographic data including age, sex, and height were gathered from the patients' records, and patients were questioned about symptoms of Eagle's syndrome before trauma. Data were analyzed using SPSS version 20 with the methods of t-test, Chi-square, and ANOVA. P < 0.05 was considered statistically significant.Results:Two-hundred and sixteen males and 177 females underwent MDCT. The length of right, left, and mean length of both sides were 25.4 ± 7.3, 25.2 ± 7.8, 25.3 ± 7.1, respectively. The mean length of both sides' process was more among male that was statistically significant (P = 0.025 and 0.043, respectively). Right and left side styloid process' higher length was in correlation with patient's height (P = 0.002, r = 0.153, P = 0.029, r = 0.110, respectively) and number of symptoms (P < 0.001, r = 0.300, P < 0.001, r = 0.334, respectively).Conclusion:The mean length of styloid process was 25.3 ± 7.1 that was in accordance with some studies and different from others. Styloid process length is higher in males. The length of styloid process is in association with height and number of symptoms as well.
BackgroundPolycystic ovarian syndrome (PCOS) is one of the most common endocrinopathies and metabolic disorders in women during their reproductive years and is often associated with dyslipidaemia and other cardiovascular diseases (CVD) risk factors. This study aimed to evaluate the effects of dietary intervention with canola and olive oils in comparison with sunflower oil on lipid profile and fatty liver severity among women with PCOS.MethodThis study was a 10 weeks intervention including 72 women with PCOS. Patients were randomly assigned to three groups to receive 25 g/day canola, olive, or sunflower oils for 10 weeks. The primary outcome was any changes in the lipid profile and the secondary outcome was a change in fatty liver severity.ResultAt the end of the study, 72 patients with a mean age of 29.31 were analyzed. Canola oil consumption led to a significant reduction in serum levels of triglycerides and TC/HDL (p = 0.021), LDL/HDL (p = 0.047), and TG/HDL (p = 0.001) ratios, but there was no significant reduction in lipid profile following olive oil consumption. Moreover, both the canola (p < 0.001) and olive oils (p = 0.005) could significantly reduce the fatty liver grade.ConclusionOverall, compared to the olive and sunflower oils, significant improvements in lipid profile and liver function were observed following consumption of canola oil in women with PCOS.Trial registrationIR.MUI.RESEARCH.REC.1397.315. Registered 30 JUNE 2019 - Retrospectively registered, https://www.irct.ir/trial/38684
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