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Introduction: Heart failure(HF) related hospitalization constitutes a significant proportion of healthcare cost. Unchanging rates of readmission during recent years, shows the importance of addressing this problem. Methods: Patients admitted with heart failure diagnosis in our institution during April 2018to August 2018 were selected. Clinical, para-clinical and imaging data were recorded. All included patients were followed up for 6 months. The primary endpoints of the study were prevalence of early readmission and the predictors of that. Secondary end points were in-hospital and 6-month post-discharge mortality rate and late readmission rate. Results: After excluding 94 patients due to missing data, 428 patients were selected. Mean age of patients was 58.5 years (±17.4) and 61% of patients were male. During follow-up, 99patients (24%) were readmitted. Early re-admission (30-day) occurred in 27 of the patients(6.6%). The predictors of readmission were older age ( P=0.006), lower LVEF (P <0.0001), higher body weight (P=0.01), ICD/CRT implantation ( P=0.001), Lower sodium ( P=0.01), higher Pro-BNP(P=0.01), Higher WBC count (P=0.01) and higher BUN level (P=0.02). Independent predictors of early readmission were history of device implantation (P=0.007), lower LVEF (P=0.016), QRS duration more than 120 ms (P=0.037), higher levels of BUN (P=0.008), higher levels of Pro-BNP(P=0.037) and higher levels of uric acid (P=0.035). Secondary end points including in-hospital and 6-month post-discharge mortality occurred in 11% and 14.4% of patients respectively. Conclusion: Lower age of our heart failure patients and high prevalence of ischemic cardiomyopathy, necessitate focusing on more preventable factors related to heart failure.

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Background: Pulmonary hypertension is a rare and fatal disease and several methods are available for its risk stratification. Right heart catheterization is gold standard tool for this target but this method is invasive and expensive. Serum uric acid level is a controversial method for this aim. Objectives: This paper aims to discover a correlation between serum uric acid level and severity of pulmonary hypertension based on right heart catheterization. Methods: Uric acid level was measured in 128 pulmonary hypertension patients who had undergone right heart catheterization. Then, the correlations between uric acid level and right heart catheterization findings as well as pulmonary hypertension severity were assessed. Results: The correlations between serum uric acid level and CI (P = 0.019), DAP (P = 0.032), MAP (P = 0.027), RAP (P = 0.002), SPAP (P = 0.015), MPAP (P = 0.035), PPPA (P = 0.011), SO2S (P = 0.005), MVO2S (P = 0.004) are significant. A positive correlation was found between serum uric acid level and pulmonary hypertension risk based on RAP (P = 0.006) and MVO2S (P = 0.022). Conclusions: It was found that the serum uric acid level is significantly correlated with some parameters of right heart catheterization including CI, DAP, MAP, SPAP, MPAP, PPPA, especially RAP, SO2S and MVO2S. Also uric acid level is significantly correlated with severity of pulmonary hypertension based on RAP and MVO2S and the level is increased in high risk ranked patients.