Identity Protein DescriptionA transmembrane glycoprotein of 532 amino acids, which has a molecular mass ranging from 75 to 115 kDa. ICAM-1 is a member of the immunoglobulin supergenge family, and contains five extracellular immunoglobulin-like domains.

No abstract

No abstract

No abstract

Daxx was originally identified as a protein factor that binds to a transmembrane receptor called Fas (FAS/APO-1/CD95), one member of the ▶ tumor necrosis factor receptor superfamily (Yang et al. 1997). The extracellular region of Fas is where its ligand, FasL, binds. The intracellular tail shares sequence similarity with another member of the TNF receptor family, TNF receptor I (TNFRI). The shared sequence is termed death domain for its critical role in signaling cell death upon ligand binding.