Uterine cervix and corpus are rarely the initial site of relapse in leukemia or lymphoma. We report herein a case of uterine cervical relapse with B-cell acute lymphoblastic leukemia (ALL). The patient, a 60-yr-old woman, had a history of ALL that had been in remission for 2 yr after chemotherapy. She presented with a chief complaint of genital bleeding. In a routine cervico-vaginal Papanicolau smear, abundant atypical lymphoid cells with round-to-oval nuclei, scant cytoplasm, and high nuclear to cytoplasmic ratios was observed. The nuclei of these cells had fine and dark chromatin and thickened nuclear membranes, with one or several nucleoli being visible. Biopsy under colposcope was performed, and a diagnosis of relapse of ALL was confirmed. The ongoing genital bleeding presented a problem with clinical management of the patient. It was decided to proceed with hysterectomy to end that problem and thereafter proceed with therapy directed against the leukemia. Our results suggest that in patients with known extrauterine cancer, the presence of malignancy in uterine cellular samples provides information regarding the extent of the neoplasm.

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Shohei IWAO * and Masami ASANO * SWAAT for 20 days has been carried out on brazing sheets of 1 mm thickness to estimate outside corrosion resistance on the material for aluminum heat exchanger applied at higher temperature. Maximum corrosion depth after the test decreased in brazing sheets both of Al-1%Mn alloy core and of Al-1%Mn-0.5%Si alloy core clad with Al-Si alloy filler while it increased in that of Al-1%Mn-0.5%Si-0.5%Cu alloy core, with increase of heat treatment time at 200°C after brazing. Marked intergranular corrosion in the core was observed in the latter alloy. On the other hand, general corrosion was observed in brazing sheets clad with filler alloy containing Zn, and the attack stopped at near interface between filler and core, independent of core alloys and of heat treatment time. Corrosion characteristics and attack depth on the sheets were discussed in terms of electrochemical properties of filler and core alloys.

To facilitate timely removal of urinary catheters and promote self-voiding among inpatients, urinary care teams have been established in some Japanese medical institutions. However, direct evidence of the effectiveness of pharmacist intervention in urinary care teams is limited. We evaluated the efficacy of pharmaceutical support by a pharmacist in a urinary care team. Between September 2017 and August 2018, 84 patients met the criteria for initiating continuous intervention. Patients with (20 cases) and without (8 cases) adoption of pharmaceutical support (initiation or discontinuation of treatment for dysuria) were scored for urinary function (including degree of independence of urination and score of lower urinary tract disorder) and for urinary situation. Comparative analysis results showed that pharmacist intervention in the adoption cases resulted in significantly improved scores for urinary function than in non-adoption cases. Similarly, pharmaceutical support resulted in improved overall urinary situation in the patients (85.0% of adoption cases compared to 37.5% of the non-adoption cases). The most common pharmaceutical support was a recommendation to discontinue drugs that induce dysuria (65.0% of the cases). Taken together, our findings suggested that pharmacists are important members of urinary care teams.

Effects of chemical composition and cold reduction on sagging resistance of Al-Mn alloys core brazing sheets were examined. Sagging resistance was controlled by recrystallization structure of the core during brazing. The best resistance was obtained in the sheets of about 30% cold reduction in which unisotropic coarser grains with no subgrain were formed. Zr addition in the core was effective to improve the resistance. Effect of the factors was discussed in terms of annealing characteristics. To obtain excellent sagging resistance full annealing temperature of the core has to be as high as possible, but to be lower than melting point of the cladding alloy.Keywords: brazing sheet, sagging resistance, AI-Mn alloys (Received June 3, 1986)