MR images of four patients with a thickened filum terminale showing a fat signal are presented. There were no related symptoms and no evidence of tethering. The thickened fatty filum terminale seemed to be a developmental anomaly and without clinical significance. As the incidence of this anomaly was 0.24% in our series, knowledge of its possible presence of this anomaly is important for routine reviews of MR image.

Magnetic resonance (MR) imaging of wallerian degeneration in the brain stem was studied in 30 hemiplegic patients within 12 months of ictus. As early as 25 days after the ictus, decreased signal intensities on proton-density(PD)-weighted images were observed in the brain stem ipsilaterally. This hypointensity gradually approached an isointense stage during 70-80 days after the ictus, abnormal intensities were not detected in any pulse sequence. We termed this phenomenon "Fogging effect of wallerian degeneration". In later stages, at least 81 days after the ictus, increased signal intensities on T2-weighted images, with or without decreased signal intensities on T1-weighted images, were observed in the brain stem, ipsilaterally. Finally, at least six months after the ictus, mild shrinkage of the ipsilateral brain stem was newly detected on the T1-weighted images. MR imaging has proven to be a sensitive diagnostic modality for evaluating wallerian degeneration in the brain stem.

Indirect findings of radionuclide cisternography, especially early visualization of bladder activity, may be useful in the diagnosis and posttreatment follow-up of CSF leakage.

Nine compounds (1-9) were isolated from the fruiting bodies of Stropharia rugosoannulata. Compounds 1-5, 8, and 9 suppressed the formation of osteoclast. Compounds 2 and 5 showed anti-fungal activity, and their MIC were 250 µM and 500 µM respectively. Compounds 2-6 showed inhibitory effects on thapsigargin toxicity.

Source 3D FSE images of MR myelography seem useful in the detection of CSF leakage. Invasive radionuclide cisternography may be reserved for equivocal cases only.