Orthodontic archwires, especially nickel-titanium (NiTi) ones, are a major source of nickel release. Despite their importance, no in vivo studies have assessed the ion release from conventional or new generations of NiTi archwires (copper-included and epoxy-coated). This double-blind parallel randomized clinical trial was done on 84 saliva specimens sampled at two time points from 42 orthodontic patients. The patients were randomly divided into three groups of NiTi, copper NiTi (NiTiCu), and epoxy NiTi archwires (n = 14 each). The effects of 2-month treatment, wire types, gender, and age on pretreatment, posttreatment, and time-dependent differences were analyzed statistically (α = 0.05). Salivary nickel concentrations were 10.4571 ± 0.77168 and 11.0779 ± 0.81232 μg/L, respectively, in the baseline and second month. This increase was significant (P = 0.0000, paired t test). The extents of nickel increase in different groups were 0.8279 ± 0.14 (NiTi), 0.6493 ± 0.10 (NiTiCu), and 0.385 ± 0.11 (epoxy-coated NiTi) μg/L (P = 0.0000, one-way analyses of variance (ANOVA)). Differences between each two archwire types were significant (P = 0.000, Tukey). Age and gender did not play a role. It can be concluded that NiTi archwires might increase nickel salivary levels. Epoxy-coated NiTi followed by copper NiTi archwires might release less nickel compared to conventional NiTi ones.

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The study was self-funded by the authors.

Introduction: nowadays, one of the remarkable issues in dentistry is jaw growth pattern and tooth and mouth conditions (oral conditions) on patients’ quality of life and daily activities. This study was done to evaluate skeletal malocclusion effect on the quality of life and oral health in Ahvaz. Methods: 80 people with skeletal malocclusion and 80 people with normal skeletal occlusion (control) participated in this cross-sectional study. Data collection tools included: demographic and oral health impact questionnaires. Results: there is not any significant difference between average quality of life of people with Cl III and Cl II skeletal (p=0.761), but there is a meaningful relation between Cl II skeletal and normal skeletal groups and also between Cl III skeletal and normal skeletal groups (p<0.001). Conclusion: according to social and moral issues importance in raising the quality of life score and because study results showed that these patients are not in good condition of that, considering different moral and social aspects of oral condition in presenting dentistry services are suggested to develop general quality of life