Introduction In the past decade, podcasting has become an increasingly utilized form of asynchronous education amongst medical trainees. Medical education podcasts increase accessibility of novel literature, provide entertainment and promote community. Data on the impact of medical student-run podcasts is limited. The UnsCripted Medicine Podcast (UMP) is a medical student-run podcast created to provide near-peer support, promote academic success, and strengthen sense of belongingness. This study examined UMP listener self-reported behaviors, enjoyability, and podcast efficacy as a comradery-building tool. Methods A voluntary, seventeen-question survey was disseminated to all medical students at the University of Cincinnati College of Medicine. The survey utilized Likert scale items, multiple choice, multiple answer and open-ended formats. Descriptive statistics were used for analysis. Results 143 (n = 19.5%) responses were received. Most respondents had listened to either 3–5 or 5–10 episodes (n = 51 or 41.8% and n = 36 or 29.5%, respectively). Most listeners consumed curriculum-related episodes (n = 109, 89.3%). 96% (n = 96 of 100) of listeners reported an increased sense of preparedness for courses, and 76.8% (n = 76 of 99) of listeners reported reduced stress. The UMP was considered enjoyable (n = 112 of 116, 96.5%) and was associated with an increased sense of belonging within the medical school community (n = 68 of 116, 58.6%). Discussion Medical student-run podcasts provide novel opportunities to increase near-peer mentorship within undergraduate medical education. They show promise in decreasing stress, increasing preparedness and increasing sense of belonging. Given the increasing popularity of podcasting in medical education, student podcast initiatives should be supported by medical schools.