Background Multiple sclerosis (MS) is a neurodegenerative disease of the central nervous system. MS is significantly associated with a high rate of psychological, behavioral, and emotional consequences. Despite the frequent mental disorders, high rate of psychological comorbidities, and emotional problems in people with MS (PwMS), these conditions are often underdiagnosed and undertreated. This study aimed to examine the efficacy of a group format of the unified protocol for the transdiagnostic treatment of emotional disorders in adult PwMS associated with an emotional disorder. Methods Seventy adult PwMS were randomized using an internet-based computer system to either the unified protocol (n = 35) or treatment as usual condition. The assessment protocol included semi-structured clinical interviews and self-reports evaluating diagnostic criteria, depression, anxiety and worry symptoms, emotional dysregulation, and affectivity. Results The parametric test of analysis of covariance, followed the intent to treat analyses, revealed the unified protocol significantly changed depression symptoms (Cohen’s d = 1.9), anxiety symptoms (Cohen’s d = 2.16), worry symptoms (Cohen’s d = 1.27), emotion dysregulation (Cohen’s d = 0.44), positive affect (Cohen’s d = 1.51), and negative affect (Cohen’s d = 1.89) compared with the control group. The unified protocol also significantly improved outcome scores at the end of treatment relative to baseline (p < .001). Conclusion The findings support that the unified protocol could be an additional efficient psychological treatment for PwMS. Trial registration IRCT, number: IRCT20190711044173N1. Registered 31october 2019, https://en.irct.ir/user/trial/40779/view.

Introduction: Academic satisfaction is one of the factors that can affect the whole life and fate of students. The purpose of this study was to investigate mediating effect of Academic Emotion on the relationship between basic psychological needs and academic satisfaction of students. Methods: This is a descriptive-analytic study of correlation type on all students of Yazd Shahid Sadoughi University of Medical Sciences (n=5363) during the academic year of 2018-19. The sample size was 358 (58.96% female and 41.03% male) according to Morgan table and they were selected by cluster random sampling. Research instruments were Deci and Ryan's Basic Psychological Needs, Pekrun and et al Academic Emotion scale, Lent and et al Academic Satisfaction. Data were analyzed using Pearson correlation coefficient and path analysis through AMOS and SPSS. Results: There was a positive significant relationship among basic psychological needs, positive academic emotions and academic satisfaction (P<0.01). There was a Negative significant relationship between negative academic emotions and academic satisfaction (P<0.01). The results showed that the proposed model has good fit (GFI=0.99 & RAMSEA=0.043). Path analysis results indicated that autonomy, competence and positive & negative academic emotions was significantly related to Academic satisfaction. Furthermore, the results showed that academic Emotion mediated the relationship between basic psychological needs and Academic satisfaction. Conclusion: These results show the importance of basic psychological needs, therefore to improve Academic satisfaction students must feel autonomous, competent, and experience a genuine connection with their college, lecturers and fellow students.

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