Stretchable nanocomposites-based strain gauges have received much attention due to their adjustable properties in various applications, including soft robotics, human health monitoring, body motion detection, structural health monitoring, and artificial intelligence. Although low sensitivity (gauge factor) is one of the challenges of capacitive strain gauges, in this study, we design, manufacture, and illustrate characterizations of a stretchable interdigitated capacitive strain gauge based on carbon nanofiber/ polyaniline/ silicone rubber nanocomposite by an improvement in sensitivity with linearity, and low hysteresis. This strain gauge reaches a gauge factor of about 14 over an applied strain of 2% and about 2.8 over an applied strain of 20% and demonstrates linearity with negligible hysteresis. The sensitivity of the strain sensor is enhanced not only by the interdigitated design of electrodes but also by the electrodes' outstanding electrical conductivity, even in a large strain. Due to its sensitivity, the proposed device is suitable for detecting small and large strains and can be used in wearable applications or straight on the skin for human motion detection.

C-reactive protein (CRP), an acute-phase protein synthesized in the liver in response to inflammation, is one of the biomarkers used for the detection of several diseases. Sepsis and cardiovascular diseases are two of the most important diseases for which detection of CRP at very early stages in the clinical range can help avert serious consequences. Here, a CNT-based nanobiosensing system, which is portable and reproducible, is used for label-free, online detection of CRP. The system consists of an aptameric CNT-based field-effect transistor benefiting from a buried gate geometry with Al 2 O 3 as a high dielectric layer and can reflect the pro-cytokine concentration. Test results show that the device responds to CRP changes within 8 min, with a limit of detection as low as 150 pM (0.017 mg L –1 ). The device was found to have a linear behavior in the range of 0.43–42.86 nM (0.05–5 mg L –1 ). The selectivity of the device was tested with TNF-α, IL-6, and BSA, to which the nanosensing system showed no significant response compared with CRP. The device showed good stability for 14 days and was completely reproducible during this period. These findings indicate that the proposed portable system is a potential candidate for CRP measurements in the clinical range.