The aim of this work was to study different hybrid photovoltaic-thermal (PVT) collectors. Numerical simulation of the collectors was carried out using a 3-dimensional computational fluid dynamic (CFD) model. A set of experiments was conducted using a box-type PVT collector to validate the obtained computed data. Simulation results for water outlet temperature, especially at the lower flow rates, were closer to the measured data compared with average module surface temperature. Based on the simulation results, the spiral flow designs of heat exchanger provided the most uniform temperature distribution for module surface and the highest temperature gradient was observed with the direct flow designs. A hot zone was generated on the module surface of the direct flow box-type collector and the results indicated that the hot zone was considerably declined using cross-fins inside the box-type heat exchanger. The highest heat transfer to the ambient occurred with the spiral flow design and the box type heat exchanger presented a relatively low heat losses. The cross-fined box type and the spiral flow designs of the PVT collector had the highest electrical efficiencies at the different test conditions.