Nowadays, researchers are stating that, in most cases, standard semen analyses on their own cannot discern the fertile from the infertile populations, and therefore, in addition to semen analysis, assessment of sperm functional tests, including sperm DNA damage, may assist clinicians in achieving this goal (Rocca et al., 2016).Telomeres are conserved repetitive DNA sequences found at the ends of chromosomes and play an important role in maintaining genomic integrity, chromosome pairing, and homologous chromosome synapsis. In addition, these sequences prevent chromosome end joining and facilitate meiosis II segregation. Telomeres are made up of noncoding hexameric tandem repeats (5′-TTAGGG-3′) of DNA and are linked to proteins at the chromosome's end (Li et al., 2017;Turner et al., 2019). The length of telomeres in somatic cells shortens with each cycle of cell division, and this shortening may be accelerated by diseases (cancers, obesity, diabetes and cardiovascular disease), smoking, social interaction, mental health conditions,