The aim of this pilot study was to evaluate the efficacy of the new Self-Attachment Technique (SAT) in treating resistant anxiety and depression, lasting at least three years, among Iranian women from different social backgrounds. In this self-administrable and algorithmic intervention, the participant, using their childhood photos, imaginatively creates an affectional bond with their childhood self, vows to consistently support and lovingly re-raise this child to emotional well-being. We conducted a longitudinal study with repeated measurement to evaluate the efficacy of SAT using ANOVA. Thirty-eight women satisfying the inclusion and exclusion criteria were recruited from different parts of Tehran. To describe the SAT protocols, a total of eight one-to-one sessions were offered to the recruits, the first four were weekly while the last four were fortnightly. The participants were expected to practice the protocols for twenty minutes twice a day. Two questionnaires, GAD-7 and PHQ-9, were used to measure anxiety and depression levels before and after the intervention and in a three-month follow-up. Thirty women completed the course. The change in anxiety level between the pre-test and the post-test was significant at p < 0.001 with effect size 2.5. The change in anxiety between pre-test and follow-up test was also significant at p < 0.001 with effect size 3.5. The change in anxiety between the post-test and the follow-up was significant at p < 0.05 with effect size 0.6. For depression, the changes between pre-test and post-test as well as between pre-test and follow-up were significant at p < 0.001 with effect size 2.3 and 3.1 respectively.