Aims To evaluate the role of soft tissue and ligaments damage and level of pelvic muscles activation versus intra‐abdominal pressure, on pelvic organ prolapse. Methods This was a computational modeling based on the finite element analysis. Three pelvic muscles, four pelvic ligaments, and three organs (urethra, vagina, and rectum) were simulated. The model was subjected to total 41 472 analysis cases including three intra‐abdominal pressures, two damaging levels for the ligaments, three damaging levels for the muscles, and four intentional levels of activation for muscles. Results Increased intra‐abdominal pressures caused significant statistical increase of the pelvic organ prolapse (P = 0.000) up to 10 mm downward. Ligaments’ defect had no statistically‐significant effect on prolapse of the organs (P = 0.981 for rectum, P = 0.423 for urethra, and P = 0.752 for vagina). Damage in the pelvic floor muscles and low intentional level of activation also deteriorated the prolapse (P = 0.000). Conclusion Increase of the intra‐abdominal pressure (IAP) as may be existed during pregnancy or physical activity increased the organ prolapse. Damages of the ligaments caused less effects on the prolapse. Loss of the passive properties of the muscles which is probable after delivery or aging moderately deteriorated the prolapse disorder. However, activation of the pelvic floor muscles prevented the prolapse. Different recruitments of the muscles, specifically the pubococcygeus (PCM), could compensate the possible defects in other tissues. Targeted pelvic floor muscle training (PFMT) could also be effective in older adults due to considerable role of the pelvic muscles’ intentional activation.
Background: Consumption of hot substances may harm the surrounding bone around a dental implant. High temperatures at the bone-implant interface (BII) interferes with local cellular activities involved in the osteointegration. Objectives: The present study was aimed at calculating the temperature distribution through the BII and the jaw bone under application of a transient cyclic thermal load. Methods: In this numerical simulation, finite element method was employed in a commercialized dental implant model drawn by computer-aided design tools based on CT data to find the temperature in superficial and deep bone regions near the BII. The heat load was applied cyclically during the intake time. Results: Results showed that the highest temperature was occurred at the top regions of the interface by magnitude of 48 C. Removal of the thermal loads also was followed by rapid decrease in the bone temperature. Conclusions: Routine beverages of a hot liquid can increase the temperature of the bone beyond the biological thresholds of the bone cells vitality or remodeling functionality, specifically in the delayed loading types of implantation.
Introduction: Urinary incontinence (UI) is a multifactorial and prevalent disorder among aged women. Physical activities are believed to have challenging roles in the deterioration of the UI. The aim of this study was to examine the effect of standardized weightlifting on urodynamic parameters in the urinary continent and incontinent individuals. Methods: Twenty-four UI morbid and 21 control subjects participated in a standardized weightlifting task while undergoing multichannel cystometry tests in two empty and full bladder conditions. Maximum weightlifting force (MWF) and vesical and abdominal pressures (APs) were measured to calculate the detrusor pressure. Results: Findings showed that the UI participants with full bladder have significant higher abdominal, vesical and detrusor pressures in comparison to the controls; but in empty bladder condition, only the AP of the UI morbid group was significantly greater. The MWF was not significantly changed between the UI and control groups. The MWF was also not correlated with the detrusor pressure among the UI participants and full bladder controls. Conclusion: Weightlifting till the subject's maximum force can neither produce incontinence in healthy subjects nor deteriorate the UI patients' conditions.
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