A 3ª edição do Congresso Internacional de Estudantes e Profissionais da Saúde – DELTA SAÚDE, realizou-se de forma presencial no período de 04 a 06 de novembro de 2022, no Centro de Convenções do Hotel SESC Praia, Luis Correia, Piauí. O Delta Saúde 2022 trouxe como tema geral: “O pós-pandemia e os principais desafios da saúde global”; e as discussões foram norteadas pelos eixos centrais, a saber: a) Pandemia de COVID-19, b) Vigilância em Saúde, c) Saúde Pública e a Atenção Primária, d) Saúde Mental, e) Doenças Crônicas e Doenças Transmissíveis, f) Educação, Formação e Trabalho na Saúde, g) Inovação em Saúde, h) Eixos Transversais. O evento foi criado em 2017 e nesta edição alcançamos pelo menos 10 estados brasileiros em participação direta, palestrantes, convidados, além dos conferencistas internacionais on-line. Esta diversidade aliada a qualidade dos trabalhos apresentados, contribuiu de forma decisiva para o alcance dos objetivos do congresso que primam pela qualificação do ensino na saúde de acadêmicos e pósgraduandos, pelo fortalecimento das práticas profissionais nos serviços de saúde, e pelo incentivo à produção científica. A programação do evento foi composta por palestras nacionais e internacionais, mesas multidisciplinares, cursos livres, seminários, rodas de conversas, encontros e sessões de trabalhos com apresentações nas modalidades: Comunicações Orais e Pôsteres; e com publicação das pesquisas científicas nos Anais do congresso. O evento contou com 692 inscritos, e destes 42 foram palestrantes que abrilhantaram a programação do congresso. Recebemos 746 resumos para avaliação, e foram apresentados presencialmente 536 trabalhos, sendo 42 premiados com menção honrosa. O evento foi idealizado pela Sociedade Delta Científica e SBCSaúde, teve o apoio do SESC-PI e da Doity, além do apoio científico da FIOCRUZ Piauí, da Editora Pasteur, dos núcleos de pesquisa NUPCelt/UFPI, NAPsiTO/UFPI/UFDPar e NPPM/UFPI; e dos programas de residência multiprofissional RMSFC/UESPI e PRMSF/UFPI/UFDPar. O evento também contou com a parceria de empresas patrocinadoras e expositoras, que tiveram da Comissão Organizadora reciprocidade em suas demandas, a saber: Instituto UniEducacional, WM Saúde e The Nutri Store/PACCO.

The coast of Piauí state, unexplored regarding its phytodiversity, instigates conducting research that contributes to the knowledge of its flora. This study aims to better understand the floristic diversity of a patch of vegetation in the village of Curral Velho (02º 52' 45" S and 41° 40' 01" W), in the municipality of Luís Correia, Piauí state. Random monthly samples were collected in the study area over eight months; 105 specimens were collected and 93 species belonging to 76 genera and 33 families were identified. Local flora includes floristic elements of Caatinga, Cerrado and Restinga, suggesting that the plant community in the coastal area of Piauí has a transitional nature. This study brings unpublished data on the floristic diversity of the studied area, contributing, ultimately, to the knowledge of the flora in the state as a whole. This is a pioneer and partial inventory in this portion of the state and does not portray its full phytodiversity, thus subsequent surveys are required to add data for a better knowledge on the flora in the studied stretch.

Wounds are a serious public health problem and tissue healing is a complex process that requires clinical intervention. Thus, the use of biomolecules, mainly extracted from plants, presents itself as an alternative that facilitates the innate mechanisms of tissue repair. Among the different species, it is possible to highlight the Pilocarpus microphyllus, commonly known as jaborandi, which has the imidazolic alkaloid epiisopiloturin (EPI) which has emerged in research due to its anthelmintic, anti-inflammatory and antinociceptive action. Therefore, this article aims to carry out a scientific and technological prospection of P. microphyllus and EPI focused on the treatment of wounds on publication sites and articles and national and international patents deposits. For this, a survey was carried out in the following databases: Scientific Electronic Library Online (SciELO), PubMed and Web of ScienceTM for articles and the National Institute of Industrial Property of Brazil (INPI), Latin American Patent Bank (LATIPAT), European Patent Office (EPO), World Intellectual Property Organization (WIPO) and United States Patent and Trademark Office (USPTO) for patents. The search was carried out from October to November 2021, the following descriptors were used: “Pilocarpus microphyllus”, “epiisopilloturin”, “anti-inflammatory”, “in silico” and “wounds” according to the Descriptors in Sciences of Health (DeCs), as well as combinations were performed using the Boolean operator “and”. From the articles it was possible to observe that there is no published study with the use of P. microphyllus or EPI for the treatment of wounds, however they reinforce its anti-inflammatory, antinociceptive and anthelmintic activity. In addition, conducting research in silico has emerged in recent years, expanding the field of research. In patent searches for “Pilocarpus microphyllus”, the classification that registered the highest number of deposits in technological prospecting was CIP A61K, with 68.6% frequency, followed by A01N (6.9%), C07D (5.8%) , A01H (3.4%), C12N (3.4%), A61P (2.3%), A23G (2.3%), C12P (2.3%), C07K (1.1%), A23L (1.1%), A61L (1.1%), A01P (1.1%), respectively. It is noteworthy that the largest number of patents are filed in section A (human needs) and section C (chemistry and metallurgy) of the CIP, totaling 75 and 11 records, respectively. Therefore, the use of P. mycrophyllus and EPI in the development of drugs to be used in the treatment of wounds is a promising scenario for further studies due to their biological activities, which are already well described in the scientific literature.

Recently, there is strong evidence for the beneficial role of antioxidants in the treatment of periodontal diseases. A drug that is gaining more and more focus in new research is N-acetylcysteine, an antioxidant that contributes to the increase in glutathione (GSH), used as a mucolytic agent, however, recent studies have shown its significant role in decreasing levels of reactive oxygen species and in the bone resorption process in experimental periodontitis, therefore, this review sought to elucidate whether N-acetylcysteine is effective in the treatment of periodontitis and also in the involved mechanisms already mentioned in the literature. The present study is a mini-review, in which a search was performed on Google Scholar, PubMed and Web of Science and databases for the collection of studies published in the last 10 years (2009-2020). The mini-review included studies that addressed a direct or indirect link between the effects of N-acetylcysteine on periodontitis, studies published in recent years, and in vitro and in vivo studies (animal and / or human models). Seven articles were selected from the following databases: PubMed (03) and Google Scholar (04) were subsequently analyzed. As for the language and the journal, all were published in international Journals and in English. It was concluded that N-acetylcysteine was effective in bone resorption in experimental periodontitis, but further studies are suggested in order to elucidate all the mechanisms involved in the observed results.

Chromoblastomycosis (CBM) is a cutaneous or subcutaneous mycoses. The trauma occurs when the fungus is installed and is more prevalent in individuals living in tropical and subtropical regions, with earliest descriptions dating back to 1920. The diagnosis of CBM is based on the incidence of cases in the endemic areas and is commonly reached through microbiological analyses to identify the etiologic agent in clinical samples. The process for the analysis of the collected samples allows one to visualise the muriform cells, which are brown, rounded structures having crossed chambers and that can be commonly called sclerotic bodies, characterising the positive diagnosis. The objective of this review was to verify the connection of the histopathological techniques to the diagnosis of CBM.