This work describes the first thermally activated delayed fluorescence material enabling circularly polarized light emission through chiral perturbation. These new molecular architectures obtained through a scalable one-pot sequential synthetic procedure at room temperature (83% yield) display high quantum yield (up to 74%) and circularly polarized luminescence with an absolute luminescence dissymmetry factor, |glum|, of 1.3 × 10−3. These chiral molecules have been used as an emissive dopant in an organic light emitting diode exhibiting external quantum efficiency as high as 9.1%.

A robust process for the radiosynthesis of 3/5-[ 18 F]fluoropyridines has been developed by radiofluorination of iodonium triflates using K 18 F/K 2 CO 3 /K 222 complex in the presence of TEMPO. Both electronically deficient and enriched iodonium salts were readily obtained from the corresponding 3/5-iodopyridines and afforded the corresponding 3/5-[ 18 F]fluoropyridines in 6−78% yields. The concentrations of K 2 CO 3 and TEMPO were found to be crucial for the radiofluorination efficiency. The process was validated using two automated systems for the 18 F-radiolabeling of 2-chloro and 2carboxamido-5-fluoropyridines carried out in 10−20% yields.